Recent advances in research on vine tea, a potential and functional herbal tea with dihydromyricetin and myricetin as major bioactive compounds

• Published in: Journal of pharmaceutical analysis 2021-10, Vol.11 (5), p.555-563
• Main Authors: Zhang, Qili, Zhao, Yanfang, Zhang, Meiyan, Zhang, Yalu, Ji, Hongfang, Shen, Liang
• Format: Article
• Language: English
• Subjects: Acids; Antioxidants; Arthritis; Bioactive compounds; Cytokines; Diabetes mellitus; Dihydromyricetin; Disease; Flavonoids; Functional foods & nutraceuticals; Inflammation; Investigations; Kinases; Minority & ethnic groups; Molecular mechanism; Myricetin; Neuroprotection; Oxidants; Pharmacological effects; Proteins; Review Paper; Steroids; Tea; Toxicity; Tumor necrosis factor-TNF; Tumors; Vine tea
• ISSN: 2095-1779; 2214-0883
• DOI: 10.1016/j.jpha.2020.10.002

Vine tea has been used as an herbal tea by several ethnic minorities for hundreds of years in China. Flavonoids, a kind of indispensable component in a variety of nutraceutical, pharmaceutical and cosmetic applications, are identified to be the major metabolites and bioactive ingredients in vine tea. Interestingly, vine tea exhibits a wide range of significant bioactivities including anti-oxidant, anti-inflammatory, anti-tumor, antidiabetic, neuroprotective and other activities, but no toxicity. These bioactivities, to some extent, enrich the understanding about the role of vine tea in disease prevention and therapy. The health benefits of vine tea, particularly dihydromyricetin and myricetin, are widely investigated. However, there is currently no comprehensive review available on vine tea. Therefore, this report summarizes the most recent studies investigating bioactive constituents, pharmacological effects and possible mechanisms of vine tea, which will provide a better understanding about the health benefits and preclinical assessment of novel application of vine tea. [Display omitted] •Vine tea has been consumed as a folk herbal tea for hundreds of years.•Flavonoids were the major bioactive ingredients in vine tea.•Dihydromyricetin and myricetin are major bioactives in vine tea.•Vine tea exhibits a wide range of significant bioactivities.•Vine tea may be a potential, functional herbal tea.