Secondary metabolites from marine microorganisms

After 40 years of intensive research, chemistry of marine natural products has become a mature field. Since 1995, there are signals of decreased interest in the search of new metabolites from traditional sources such as macroalgae and octocorals, and the number of annual reports on marine sponges st...

Full description

Saved in:
Bibliographic Details
Published in:Anais da Academia Brasileira de Ciências 2002-03, Vol.74 (1), p.151-170
Main Author: Kelecom, Alphonse
Format: Article
Language:English
Subjects:
acetogenins
alkaloids
Animals
bacteria
Bacteria - chemistry
Bacteria - metabolism
biological activities
Biological Factors - chemistry
Biological Factors - pharmacology
despsipeptides
Eukaryota - microbiology
Fishes - microbiology
fungi
Fungi - chemistry
Fungi - metabolism
Geologic Sediments - microbiology
Invertebrates - microbiology
Multidisciplinarias (Ciencias Sociales y Humanidades)
MULTIDISCIPLINARY SCIENCES
Seawater - microbiology
terpenoids
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:After 40 years of intensive research, chemistry of marine natural products has become a mature field. Since 1995, there are signals of decreased interest in the search of new metabolites from traditional sources such as macroalgae and octocorals, and the number of annual reports on marine sponges stabilized. On the contrary, metabolites from microorganisms is a rapidly growing field, due, at least in part, to the suspicion that a number of metabolites obtained from algae and invertebrates may be produced by associated microorganisms. Studies are concerned with bacteria and fungi, isolated from seawater, sediments, algae, fish and mainly from marine invertebrates such as sponges, mollusks, tunicates, coelenterates and crustaceans. Although it is still to early to define tendencies, it may be stated that the metabolites from microorganisms are in most cases quite different from those produced by the invertebrate hosts. Nitrogenated metabolites predominate over acetate derivatives, and terpenes are uncommon. Among the latter, sesquiterpenes, diterpenes and carotenes have been isolated; among nitrogenated metabolites, amides, cyclic peptides and indole alkaloids predominate.
ISSN:0001-3765
1678-2690
0001-3765
1678-2690
DOI:10.1590/s0001-37652002000100012