Effect of Functional Groups on Protein Adsorption Performance of Membrane Adsorbers

Functional groups on support membranes are important for the preparation of high-performance membrane adsorbers (MAs). In this work, the effects of different functional groups on support membranes on the adsorption performance of MAs were studied through surface modifications such as alkali treatmen...

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Bibliographic Details
Published in:Separations 2023-03, Vol.10 (3), p.211
Main Authors: Zhang, Lifang, Yang, Jialin, Yan, Yiqing, Zhang, Weidong
Format: Article
Language:English
Subjects:
Adsorption
Amines
Cellulose
Chemical bonds
Chemical properties
Chromatography
Deposition
Dopamine
Fluorides
Functional groups
Ligands
membrane adsorber
Membranes
Molecular weight
Oxidation
Polyvinylidene fluoride
Pore size distribution
Protein adsorption
protein adsorption capacity
Proteins
Surface chemistry
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Summary:Functional groups on support membranes are important for the preparation of high-performance membrane adsorbers (MAs). In this work, the effects of different functional groups on support membranes on the adsorption performance of MAs were studied through surface modifications such as alkali treatment, oxidation treatment and polydopamine (PDA) deposition. Our experiment results indicate that chemical bonds are prone to form between C-F on PVDF membrane and amine groups on PEI, which serves to improve the protein adsorption capacity. Furthermore, PDA deposition has the potential to enhance protein adsorption capacity. Introducing a PDA layer on a support membrane with uniform pore size distribution shows potential to improve protein adsorption capacity.
ISSN:2297-8739
2297-8739
DOI:10.3390/separations10030211