Synergistic antifungal effect of fungicide and chitosan-silver nanoparticles on Neoscytalidium dimidiatum

Chitosan-silver nanoparticles (Ag@CS) as a novel drug delivery system have been developed for fungicide drug. In this study, the synergistic effect of silver nanoparticles (AgNPs), chitosan (CS), and fungicide zineb (Zi) was investigated as antifungal materials against in dragon fruit. More specific...

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Bibliographic Details
Published in:Green processing and synthesis 2018-04, Vol.7 (2), p.132-138
Main Authors: Ngoc, Uyen Thi Phan, Nguyen, Dai Hai
Format: Article
Language:English
Subjects:
Antibiotics
Antifungal activity
Chitosan
Drug delivery
Drug delivery systems
Embedding
Fourier transforms
fungicide
Fungicides
Infrared analysis
Nanomaterials
Nanoparticles
Nanotechnology
Nanotubes
Neoscytalidium dimidiatum
Pesticides
Polymers
Silver
silver nanoparticle
Synergistic effect
Thermal stability
Thermogravimetric analysis
Transmission electron microscopy
X-ray diffraction
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Summary:Chitosan-silver nanoparticles (Ag@CS) as a novel drug delivery system have been developed for fungicide drug. In this study, the synergistic effect of silver nanoparticles (AgNPs), chitosan (CS), and fungicide zineb (Zi) was investigated as antifungal materials against in dragon fruit. More specifically, Ag@CS were prepared by embedding of AgNPs in CS polymer and then combined with Zi. Transmission electron microscopy was used to confirm the morphology and size of Ag@CS. The diameter of spherical nanoparticles is around 4.11±0.37 nm. Furthermore, the formation of Ag@CS was characterized by Fourier transform infrared and X-ray diffraction analysis. The thermostability properties of these nanoparticles were also determined by thermogravimetric analysis. Especially the antifungal activity of Ag@CS has shown antifungal ability better than each component alone, analyzed by zone of inhibition method against . These results suggest the potential applications of Ag@CS in the development of nanomaterials for antibiotic application.
ISSN:2191-9542
2191-9550
DOI:10.1515/gps-2016-0206