The Dosage Effect of Laser Acupuncture at PC6 (Neiguan) on Heart Rate Variability: A Pilot Study

• Published in: Life (Basel, Switzerland) Switzerland), 2022-11, Vol.12 (12), p.1951
• Main Authors: Chang, Yi-Chuan, Chen, Chun-Ming, Lay, Ing-Shiow, Lee, Yu-Chen, Tu, Cheng-Hao
• Format: Article
• Language: English
• Subjects: Acupuncture; Angina pectoris; autonomic nerve system; Blood pressure; Cardiovascular disease; Carpal tunnel syndrome; Chinese medicine; Clinical trials; Coronary vessels; Data collection; Diabetes; Dosage; Drug dosages; energy density; Health aspects; Heart attacks; Heart beat; Heart rate; heart rate variability; Intervention; laser acupuncture; Laser therapy; Lasers; Lasers in medicine; Lasers in surgery; Measurement; Neiguan; Nerves; Parasympathetic nervous system; Performance indices; Physiology; Statistical analysis; Sympathetic nerves; Testing; Variability; Variance analysis; Vein & artery diseases; Wrist
• ISSN: 2075-1729; 2075-1729
• DOI: 10.3390/life12121951

Laser acupuncture (LA) has been more applicated in the clinical practice with good responses, but the dosage and parameter settings are still inconsistent with the arguments. This study is focused on the effect of LA on heart rate variability (HRV) with different energy density (ED). Based on the Arndt-Schulz law, we hypothesized that the effective range should fall within 0.01 to 10 J/cm of ED, and settings above 10 J/cm would perform opposite or inhibitory results. We recruited healthy adults in both sexes as subjects and choose bilateral PC6 (Neiguan) as the intervention points to observe the HRV indexes changes by an external wrist autonomic nerve system (ANS) watch on the left forearm. The data from the ANS watch, including heart rate, blood pressure, and ANS activity indexes, such as low frequency (LF), high frequency (HF), LF%, HF%, LF/HF ratio, and so on, were analyzed by the one-way ANOVA method to test the possible effect. In this study, every subject received all three different EDs of LA in a randomized order. After analyzing the data of 20 subjects, the index of HF% was upward and LF/HF ratio was downward when the ED was 7.96 J/cm . Otherwise, the strongest ED 23.87 J/cm performed the opposite reaction. Appropriately, LA intervention could affect the ANS activities, with the tendency to increase the ratio of parasympathetic and decrease the ratio of sympathetic nerve system activities with statistically significant results, and different ED interventions are consistent with Arndt-Schulz law with opposite performance below and above 10 J/cm .