Scalp eschar and neck lymphadenopathy by Rickettsia slovaca after Dermacentor marginatus tick bite case report: multidisciplinary approach to a tick-borne disease

Scalp Eschar and Neck LymphAdenopathy after Tick bite is a zoonotic non-pathogen-specific disease most commonly due to Rickettsia slovaca and Rickettsia raoultii. Diagnosis is mostly based only on epidemiological and clinical findings, without serological or molecular corroboration. We presented a c...

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Published in:BMC infectious diseases 2021-01, Vol.21 (1), p.103-4, Article 103
Main Authors: Barlozzari, Giulia, Romiti, Federico, Zini, Maurizio, Magliano, Adele, De Liberato, Claudio, Corrias, Franco, Capponi, Guglielmo, Galli, Luisa, Scarpulla, Manuela, Montagnani, Carlotta
Format: Article
Language:English
Subjects:
Animals
Antibiotics
Antibodies
Arachnids
Asthenia
Bacteria
Blood
Care and treatment
Case Report
Case reports
Causes of
Child
Children & youth
Clavicle
DEBONEL
Deoxyribonucleic acid
Dermacentor - classification
Dermacentor - microbiology
Dermacentor marginatus
Development and progression
Diagnosis
DNA
Doxycycline
Doxycycline - therapeutic use
Epidemiology
Erythema
Female
Fever
Humans
Immunoglobulin G
Lymphadenopathy
Lymphadenopathy - diagnosis
Lymphadenopathy - drug therapy
Lymphadenopathy - microbiology
Lymphatic system
Neck
Neck - microbiology
Parasitic diseases
Pathogens
Patients
Polymerase chain reaction
Rickettsia - genetics
Rickettsia - immunology
Rickettsia - isolation & purification
Rickettsia Infections - diagnosis
Rickettsia Infections - drug therapy
Rickettsia Infections - microbiology
Rickettsia slovaca
Scalp
Scalp Dermatoses - diagnosis
Scalp Dermatoses - drug therapy
Scalp Dermatoses - microbiology
SENLAT
Serology
Tick Bites - complications
Tick Bites - microbiology
Tick Bites - parasitology
Tick-borne diseases
Tick-Borne Diseases - diagnosis
Tick-Borne Diseases - drug therapy
Tick-Borne Diseases - microbiology
Tick-borne rickettsioses
Treatment Outcome
Zoonoses
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cited_by cdi_FETCH-LOGICAL-c631t-bdf1c93fdb002d3c5d13bb133193a74947a94518b0fdde15a1d8723d8603aebe3
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container_issue 1
container_start_page 103
container_title BMC infectious diseases
container_volume 21
creator Barlozzari, Giulia
Romiti, Federico
Zini, Maurizio
Magliano, Adele
De Liberato, Claudio
Corrias, Franco
Capponi, Guglielmo
Galli, Luisa
Scarpulla, Manuela
Montagnani, Carlotta
description Scalp Eschar and Neck LymphAdenopathy after Tick bite is a zoonotic non-pathogen-specific disease most commonly due to Rickettsia slovaca and Rickettsia raoultii. Diagnosis is mostly based only on epidemiological and clinical findings, without serological or molecular corroboration. We presented a clinical case in which diagnosis was supported by entomological identification and by R. slovaca DNA amplifications from the tick vector. A 6-year-old child presented with asthenia, scalp eschar and supraclavicular and lateral-cervical lymphadenopathy. Scalp Eschar and Neck LymphAdenopathy After Tick bite syndrome following a Dermacentor marginatus bite was diagnosed. Serological test on serum revealed an IgG titer of 1:1024 against spotted fever group rickettsiae, polymerase chain reaction assays on tick identified Rickettsia slovaca. Patient was successfully treated with doxycycline for 10 days. A multidisciplinary approach including epidemiological information, clinical evaluations, entomological identification and molecular investigations on tick, enabled proper diagnosis and therapy.
doi_str_mv 10.1186/s12879-021-05807-3
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Diagnosis is mostly based only on epidemiological and clinical findings, without serological or molecular corroboration. We presented a clinical case in which diagnosis was supported by entomological identification and by R. slovaca DNA amplifications from the tick vector. A 6-year-old child presented with asthenia, scalp eschar and supraclavicular and lateral-cervical lymphadenopathy. Scalp Eschar and Neck LymphAdenopathy After Tick bite syndrome following a Dermacentor marginatus bite was diagnosed. Serological test on serum revealed an IgG titer of 1:1024 against spotted fever group rickettsiae, polymerase chain reaction assays on tick identified Rickettsia slovaca. Patient was successfully treated with doxycycline for 10 days. A multidisciplinary approach including epidemiological information, clinical evaluations, entomological identification and molecular investigations on tick, enabled proper diagnosis and therapy.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>33482743</pmid><doi>10.1186/s12879-021-05807-3</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-5950-4965</orcidid><oa>free_for_read</oa></addata></record>
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1471-2334
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source Publicly Available Content (ProQuest); PubMed
subjects Animals
Antibiotics
Antibodies
Arachnids
Asthenia
Bacteria
Blood
Care and treatment
Case Report
Case reports
Causes of
Child
Children & youth
Clavicle
DEBONEL
Deoxyribonucleic acid
Dermacentor - classification
Dermacentor - microbiology
Dermacentor marginatus
Development and progression
Diagnosis
DNA
Doxycycline
Doxycycline - therapeutic use
Epidemiology
Erythema
Female
Fever
Humans
Immunoglobulin G
Lymphadenopathy
Lymphadenopathy - diagnosis
Lymphadenopathy - drug therapy
Lymphadenopathy - microbiology
Lymphatic system
Neck
Neck - microbiology
Parasitic diseases
Pathogens
Patients
Polymerase chain reaction
Rickettsia - genetics
Rickettsia - immunology
Rickettsia - isolation & purification
Rickettsia Infections - diagnosis
Rickettsia Infections - drug therapy
Rickettsia Infections - microbiology
Rickettsia slovaca
Scalp
Scalp Dermatoses - diagnosis
Scalp Dermatoses - drug therapy
Scalp Dermatoses - microbiology
SENLAT
Serology
Tick Bites - complications
Tick Bites - microbiology
Tick Bites - parasitology
Tick-borne diseases
Tick-Borne Diseases - diagnosis
Tick-Borne Diseases - drug therapy
Tick-Borne Diseases - microbiology
Tick-borne rickettsioses
Treatment Outcome
Zoonoses
title Scalp eschar and neck lymphadenopathy by Rickettsia slovaca after Dermacentor marginatus tick bite case report: multidisciplinary approach to a tick-borne disease
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