The effect of aerobic exercise on oxidative stress in patients with chronic kidney disease: a systematic review and meta-analysis with trial sequential analysis

PurposeThe purpose of this study was to investigate how aerobic exercise affects oxidative stress (OS) in patients with chronic kidney disease (CKD).MethodsRetrieval dates range from the date the database was established to 19 July 2023, without languages being restricted. A meta-analysis and sensit...

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Bibliographic Details
Published in:Renal failure 2023, Vol.45 (2), p.2252093-2252093
Main Authors: Zhao, Mengjie, Xiao, Mengli, Tan, Qin, Lyu, Jian, Lu, Fang
Format: Article
Language:English
Subjects:
Aerobic capacity
aerobic exercise
Aerobics
Antioxidants
Chronic kidney disease
Exercise
Glutathione peroxidase
Isoprostanes
Kidney diseases
Meta-analysis
Oxidative stress
Physical fitness
Review
Sensitivity analysis
State-of-the-Art Review
trial sequential analysis
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Summary:PurposeThe purpose of this study was to investigate how aerobic exercise affects oxidative stress (OS) in patients with chronic kidney disease (CKD).MethodsRetrieval dates range from the date the database was established to 19 July 2023, without languages being restricted. A meta-analysis and sensitivity analysis were conducted using RevMan 5.3 and Stata 16.0.ResultsThe meta-analysis showed that, compared to usual activity or no exercise, aerobic exercise significantly reduced the oxidative markers malondialdehyde (MDA) (mean differences (MD) − 0.96 (95% CI −1.33, − 0.59); p 
ISSN:0886-022X
1525-6049
DOI:10.1080/0886022X.2023.2252093