Theranostics Nuclear Medicine in Prostate Cancer

Theranostic Nuclear Medicine is based on the idea of combining the same molecule (or drug) with different radioisotopes for both diagnosis and treatment, a concept that emerged in the early 1940s with the use of radioactive iodine for thyroid diseases. Theranostic Nuclear Medicine has since expanded...

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Bibliographic Details
Published in:Pharmaceuticals (Basel, Switzerland) Switzerland), 2024-11, Vol.17 (11), p.1483
Main Authors: Lima, Helena, Etchebehere, Marina, Bogoni, Mateos, Torricelli, Caroline, Nogueira-Lima, Ellen, Deflon, Victor M, Lima, Mariana, Etchebehere, Elba
Format: Article
Language:English
Subjects:
177Lu-PSMA
18F-FDG
18F-fluoride
Antigens
Cancer therapies
Care and treatment
Development and progression
Diagnosis
Disease
Drug dosages
Fluorides
Health aspects
Hydroxyapatite
Metastasis
Nuclear medicine
PET/CT
Precision medicine
Prostate cancer
PSMA
Ra-223
Radiation
Radioisotopes
Radiopharmaceuticals
Review
Scintigraphy
Thyroid cancer
Tomography
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Description
Summary:Theranostic Nuclear Medicine is based on the idea of combining the same molecule (or drug) with different radioisotopes for both diagnosis and treatment, a concept that emerged in the early 1940s with the use of radioactive iodine for thyroid diseases. Theranostic Nuclear Medicine has since expanded to diseases of higher incidence, such as prostate cancer, with several imaging methods used to assess the extent of the disease and the corresponding radiopharmaceuticals used for treatment. For example, by detecting osteoblastic metastases by bone scintigraphy, corresponding radiopharmaceuticals with therapeutic properties can be administered to eliminate or reduce pain associated with metastases and/or determine overall survival gain. The purpose of this review is to discuss the role of Theranostic Nuclear Medicine in prostate cancer, addressing the main diagnostic imaging studies with their corresponding treatments in the Theranostic model.
ISSN:1424-8247
1424-8247
DOI:10.3390/ph17111483