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Synthesis and Antimicrobial Activity of Bis-4,6-sulfonamidated 5,7-Dinitrobenzofuroxans
A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7–11 had been synthesized and tested for antimicrobial activity. The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy, and mass spectrometry (MALDITOF). The synthesized compounds were...
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Published in: | Journal of chemistry 2014-01, Vol.2014 (2014), p.1-6 |
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container_title | Journal of chemistry |
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creator | Galkin, Vladimir I. Pozdeev, Oskar K. Shulaeva, Marina P. Usupova, Luiza M. Bakhtiyarova, Yuliya V. Tudriy, Elena V. Galkina, Irina V. Egorova, Svetlana N. |
description | A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7–11 had been synthesized and tested for antimicrobial activity. The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy, and mass spectrometry (MALDITOF). The synthesized compounds were tested for their in vitro antimicrobial activity using the disk diffusion method against Gram-positive bacteria Staphylococcus aureus; the Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa, and Proteus mirabilis; the fungal strain Aspergillus niger; and the yeast-like pathogenic fungus Candida albicans. Our results indicate that the compounds 7–11 exhibit potent antimicrobial activity. The stability of the compounds was evaluated by TG and DSC methods. |
doi_str_mv | 10.1155/2014/367351 |
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The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy, and mass spectrometry (MALDITOF). The synthesized compounds were tested for their in vitro antimicrobial activity using the disk diffusion method against Gram-positive bacteria Staphylococcus aureus; the Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa, and Proteus mirabilis; the fungal strain Aspergillus niger; and the yeast-like pathogenic fungus Candida albicans. Our results indicate that the compounds 7–11 exhibit potent antimicrobial activity. The stability of the compounds was evaluated by TG and DSC methods.</description><subject>Chemical properties</subject><subject>Chemical structure</subject><subject>Chemical synthesis</subject><subject>Furans</subject><subject>Methods</subject><subject>Production processes</subject><issn>2090-9063</issn><issn>2090-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqFkd1rFTEQxYMoWK598l0WfNNum9lsPvbxWr8KBR-q-BhmN0k75d5ENmn1-teb25VioWDykDD8zpnDDGMvgR8DSHnScehPhNJCwhN20PGBtwPX8PT-r8RzdpjzNa_HGCE7fcC-X-xiufKZcoPRNetYaEvTnEbCTbOeCt1S2TUpNO8ot_2RavPNJqSIW3JYvGvkkW7fU6RSJT7-TuFmTr8w5hfsWcBN9od_3xX79vHD19PP7fmXT2en6_N26hWUFtyoVQ2vhR8NDNooHgwPqKTiZgRAjS74YFTvtXKd4713k8bRcxwHr0Cs2Nni6xJe2x8zbXHe2YRk7wppvrQ4F5o23oIXgEL2fOigBy2NqT2DlH1A7NSw93q9eF1ixSmGVGactpQnu64C4FLUoCt2_AhVr_N1cin6QLX-QPB2EdSx5jz7cB8TuN1vzu43Z5fNVfrNQl9RdPiT_gO_WmBfER_wH1gMgxLiD04JnwQ</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Galkin, Vladimir I.</creator><creator>Pozdeev, Oskar K.</creator><creator>Shulaeva, Marina P.</creator><creator>Usupova, Luiza M.</creator><creator>Bakhtiyarova, Yuliya V.</creator><creator>Tudriy, Elena V.</creator><creator>Galkina, Irina V.</creator><creator>Egorova, Svetlana N.</creator><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>DOA</scope></search><sort><creationdate>20140101</creationdate><title>Synthesis and Antimicrobial Activity of Bis-4,6-sulfonamidated 5,7-Dinitrobenzofuroxans</title><author>Galkin, Vladimir I. ; Pozdeev, Oskar K. ; Shulaeva, Marina P. ; Usupova, Luiza M. ; Bakhtiyarova, Yuliya V. ; Tudriy, Elena V. ; Galkina, Irina V. ; Egorova, Svetlana N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-1db7615573eb8197860f80fa65608b11a7adfef864e76d2d04edc7abe0ab9e613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Chemical properties</topic><topic>Chemical structure</topic><topic>Chemical synthesis</topic><topic>Furans</topic><topic>Methods</topic><topic>Production processes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Galkin, Vladimir I.</creatorcontrib><creatorcontrib>Pozdeev, Oskar K.</creatorcontrib><creatorcontrib>Shulaeva, Marina P.</creatorcontrib><creatorcontrib>Usupova, Luiza M.</creatorcontrib><creatorcontrib>Bakhtiyarova, Yuliya V.</creatorcontrib><creatorcontrib>Tudriy, Elena V.</creatorcontrib><creatorcontrib>Galkina, Irina V.</creatorcontrib><creatorcontrib>Egorova, Svetlana N.</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access Journals</collection><collection>CrossRef</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Galkin, Vladimir I.</au><au>Pozdeev, Oskar K.</au><au>Shulaeva, Marina P.</au><au>Usupova, Luiza M.</au><au>Bakhtiyarova, Yuliya V.</au><au>Tudriy, Elena V.</au><au>Galkina, Irina V.</au><au>Egorova, Svetlana N.</au><au>Rao, Pasupuleti Visweswara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and Antimicrobial Activity of Bis-4,6-sulfonamidated 5,7-Dinitrobenzofuroxans</atitle><jtitle>Journal of chemistry</jtitle><date>2014-01-01</date><risdate>2014</risdate><volume>2014</volume><issue>2014</issue><spage>1</spage><epage>6</epage><pages>1-6</pages><issn>2090-9063</issn><eissn>2090-9071</eissn><abstract>A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7–11 had been synthesized and tested for antimicrobial activity. 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subjects | Chemical properties Chemical structure Chemical synthesis Furans Methods Production processes |
title | Synthesis and Antimicrobial Activity of Bis-4,6-sulfonamidated 5,7-Dinitrobenzofuroxans |
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