Risk factors for sustained virological non-suppression among children and adolescents living with HIV in Zimbabwe and Malawi: a secondary data analysis

We investigated risk factors for sustained virological non-suppression (viral load ≥ 1000 copies/ml on two tests 48 weeks apart) among children and adolescents accessing HIV care in public sector clinics in Harare, Zimbabwe and Blantyre, Malawi. Participants were enrolled between 2016 and 2019, were...

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Published in:BMC pediatrics 2022-06, Vol.22 (1), p.340-9, Article 340
Main Authors: Jackson, Christi, Rehman, Andrea M, McHugh, Grace, Gonzalez-Martinez, Carmen, Ngwira, Lucky G, Bandason, Tsitsi, Mujuru, Hilda, Odland, Jon O, Corbett, Elizabeth L, Ferrand, Rashida A, Simms, Victoria
Format: Article
Language:English
Subjects:
Adolescent
Age groups
Anti-HIV Agents - therapeutic use
Antiretroviral drugs
Antiretroviral therapy
Antiviral agents
Child
Chronic lung disease
Counseling
Data Analysis
Development and progression
Drug dosages
Drug therapy
Education
HIV
HIV infection in children
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV viral load
Human immunodeficiency virus
Humans
Investigations
Lung diseases
Malawi - epidemiology
Measurement
Pediatric research
Pediatrics
Resistance
Risk Factors
Sociodemographics
Teenagers
Viral Load
Viral non-suppression
Viremia
Zimbabwe - epidemiology
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Summary:We investigated risk factors for sustained virological non-suppression (viral load ≥ 1000 copies/ml on two tests 48 weeks apart) among children and adolescents accessing HIV care in public sector clinics in Harare, Zimbabwe and Blantyre, Malawi. Participants were enrolled between 2016 and 2019, were aged 6-19 years, living with HIV, had chronic lung disease (FEV z-score 
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-022-03400-4