Effect of Cholecystectomy on the Occurrence of Knee Osteoarthritis

Objective To evaluate the effect of cholecystectomy on the occurrence of knee osteoarthritis (KOA). Methods The present study was a case‐control study with a retrospective, cross‐sectional, and longitudinal study design. The clinical data for knee osteoarthritis in the Second Hospital of Shanxi Medi...

Full description

Saved in:
Bibliographic Details
Published in:Orthopaedic surgery 2020-06, Vol.12 (3), p.756-760
Main Authors: Zeng, Ling‐yuan, Yang, Shu‐yan, Zhang, Zhi‐qiang, Wang, Tao, Wang, Yu‐ze, Wei, Xiao‐chun
Format: Article
Language:English
Subjects:
Age
Alcohol
Alcohol abuse
Alcoholism
Analysis
Arthritis
Blood pressure
Body mass index
Bone density
Cardiovascular disease
Cartilage
Cholecystectomy
Clinical
Disease occurrence
Fractures
Gallbladder
Gallbladder diseases
Gender
Hospitals
Hypertension
Hysterectomy
KOA
Medical colleges
Medical records
Medical research
Medicine, Experimental
Metabolism
Orthopedics
Osteoarthritis
Osteoporosis
Patients
Regression analysis
Smoking
Statistical analysis
Subchondral trabeculae
Surgery
Vitamin D
Vitamin deficiency
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To evaluate the effect of cholecystectomy on the occurrence of knee osteoarthritis (KOA). Methods The present study was a case‐control study with a retrospective, cross‐sectional, and longitudinal study design. The clinical data for knee osteoarthritis in the Second Hospital of Shanxi Medical University from January 2016 to September 2018 was analyzed. Clinical data, including gender, age, height, weight, smoking, alcohol abuse, prior medical history, and previous surgical history, were recorded. A logistic regression model was used for the univariate and multivariate analysis. Results A total of 1659 patients with KOA (KOA group) and 1195 limb fracture patients (control group) were included in this study. Among the 1659 patients with KOA, 388 patients were male and 1271 were female, while among the 1195 patients in the control group, 638 patients were male and 557 patients were female. The period between cholecystectomy and knee osteoarthritis onset ranged from 0.5 years to 17 years; the average interval time was 8.73 ± 2.11 years. The age at disease onset was significantly older when compared to the control group, while the body mass index in the KOA group was significantly higher when compared to the control group (P 
ISSN:1757-7853
1757-7861
DOI:10.1111/os.12671