Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report

BackgroundOnly a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign.ResultsHere we report the first case of central nervous system (CNS) demyelination with systemic infla...

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Bibliographic Details
Published in:Frontiers in neurology 2022-08, Vol.13
Main Authors: Bastide, Laure, Perrotta, Gaetano, Lolli, Valentina, Mathey, Céline, Vierasu, Ortensa-Irina, Goldman, Serge, Vandergheynst, Frédéric
Format: Article
Language:English
Subjects:
acute disseminated encephalomyelitis (ADEM)
COVID-19
fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT)
Neurology
systemic inflammation
vaccination
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Summary:BackgroundOnly a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign.ResultsHere we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine.ConclusionsClinicians should stay aware of potential new adverse events after immunization.
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2022.995875