Loading…
Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening
The aim of this study is to compare specific three-institution, cross-country data that are relevant to the Global Surgery indicators and the functioning of health systems. We retrospectively reviewed the clinical and socioeconomic characteristics of pediatric patients who underwent cerebrospinal fl...
Saved in:
| Published in: | Frontiers in surgery 2021-08, Vol.8, p.704346-704346 |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43 |
| container_end_page | 704346 |
| container_issue | |
| container_start_page | 704346 |
| container_title | Frontiers in surgery |
| container_volume | 8 |
| creator | Ferraris, Kevin Paul Palabyab, Eric Paolo M Kim, Sergei Matsumura, Hideaki Yap, Maria Eufemia C Cloma-Rosales, Venus Oliva Letyagin, German Muroi, Ai Baticulon, Ronnie E Alcazaren, Jose Carlos Seng, Kenny Navarro, Joseph Erroll |
| description | The aim of this study is to compare specific three-institution, cross-country data that are relevant to the Global Surgery indicators and the functioning of health systems.
We retrospectively reviewed the clinical and socioeconomic characteristics of pediatric patients who underwent cerebrospinal fluid (CSF) diversion surgery for hydrocephalus in three different centers: the University of Tsukuba Hospital in Ibaraki, Japan (HIC), the Jose R. Reyes Memorial Medical Center in Manila, Philippines [low-to-middle-income country (LMIC)], and the Federal Neurosurgical Center in Novosibirsk, Russia (UMIC). The outcomes of interest were the timing of CSF diversion surgery and mortality. Statistical tests included descriptive statistics, Cox proportional hazards model, and logistic regression. Nation-level data were also obtained to provide the relevant socioeconomic contexts in discussing the results.
In total, 159 children were included, where 13 are from Japan, 99 are from the Philippines, and 47 are from the Russian Federation. The median time to surgery at the specific neurosurgical centers was 6 days in the Philippines and 1 day in both Japan and Russia. For the cohort from the Philippines, non-poor patients were more likely to receive CSF diversion surgery at an earlier time (HR = 4.74, 95% CI 2.34-9.61, |
| doi_str_mv | 10.3389/fsurg.2021.704346 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_1f23689dcd844c288ee7143286bd90e0</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_1f23689dcd844c288ee7143286bd90e0</doaj_id><sourcerecordid>2572213703</sourcerecordid><originalsourceid>FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43</originalsourceid><addsrcrecordid>eNpVkk1v1DAQhiMEolXpD-CCfOSSxV_54oBUIuiuVATSgsTNcuxJ1pUTL7ZTKX-E34vTLVV7GHlkv_PMePRm2VuCN4zVzYc-zH7YUEzJpsKc8fJFdk5pU-Z1Vfx--SQ_yy5DuMUYE8ZJSfnr7IzxgrCGsPPs77V1nbRon2DgF7SbtFEyOh-QnDT6AdrI6I1C20V7p-B4kHYOH9EV-jbbaBRMETxqvQshb908xcRo3XiUXkZzB2gfZ72gz7Ox2kwDigdArQyAeufRFqSNB7RfQoQxKT1MQxJMSfgme9VLG-Dy4bzIfn398rPd5jffr3ft1U2uWFPEHApGO84rzntSSIZJictSFSmANbSolVRQNUWnpOx73fUV4V2lsdaac057zi6y3YmrnbwVR29G6RfhpBH3F84PQvr0TQuC9JSVdaOVrjlXtK4BEo7Ruux0gwEn1qcT6zh3I-h1NV7aZ9DnL5M5iMHdiZrTmlTrMO8fAN79mSFEMZqgwFo5gZuDoEVFKWEVZklKTlK1bt5D_9iGYLHaQ9zbQ6z2ECd7pJp3T-d7rPhvBvYP5Pi7Aw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2572213703</pqid></control><display><type>article</type><title>Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening</title><source>PubMed Central</source><creator>Ferraris, Kevin Paul ; Palabyab, Eric Paolo M ; Kim, Sergei ; Matsumura, Hideaki ; Yap, Maria Eufemia C ; Cloma-Rosales, Venus Oliva ; Letyagin, German ; Muroi, Ai ; Baticulon, Ronnie E ; Alcazaren, Jose Carlos ; Seng, Kenny ; Navarro, Joseph Erroll</creator><creatorcontrib>Ferraris, Kevin Paul ; Palabyab, Eric Paolo M ; Kim, Sergei ; Matsumura, Hideaki ; Yap, Maria Eufemia C ; Cloma-Rosales, Venus Oliva ; Letyagin, German ; Muroi, Ai ; Baticulon, Ronnie E ; Alcazaren, Jose Carlos ; Seng, Kenny ; Navarro, Joseph Erroll</creatorcontrib><description>The aim of this study is to compare specific three-institution, cross-country data that are relevant to the Global Surgery indicators and the functioning of health systems.
We retrospectively reviewed the clinical and socioeconomic characteristics of pediatric patients who underwent cerebrospinal fluid (CSF) diversion surgery for hydrocephalus in three different centers: the University of Tsukuba Hospital in Ibaraki, Japan (HIC), the Jose R. Reyes Memorial Medical Center in Manila, Philippines [low-to-middle-income country (LMIC)], and the Federal Neurosurgical Center in Novosibirsk, Russia (UMIC). The outcomes of interest were the timing of CSF diversion surgery and mortality. Statistical tests included descriptive statistics, Cox proportional hazards model, and logistic regression. Nation-level data were also obtained to provide the relevant socioeconomic contexts in discussing the results.
In total, 159 children were included, where 13 are from Japan, 99 are from the Philippines, and 47 are from the Russian Federation. The median time to surgery at the specific neurosurgical centers was 6 days in the Philippines and 1 day in both Japan and Russia. For the cohort from the Philippines, non-poor patients were more likely to receive CSF diversion surgery at an earlier time (HR = 4.74, 95% CI 2.34-9.61,
<0.001). In the same center, those with infantile or posthemorrhagic hydrocephalus (HR = 3.72, 95% CI 1.70-8.15,
= 0.001) were more likely to receive CSF diversion earlier compared to those with congenital hydrocephalus, and those with postinfectious (HR = 0.39, 95% CI 0.22-0.70,
= 0.002) or myelomeningocele-associated hydrocephalus (HR = 0.46, 95% CI 0.22-0.95,
= 0.037) were less likely to undergo surgery at an earlier time. For Russia, older patients were more likely to receive or require early CSF diversion (HR = 1.07, 95% CI 1.01-1.14,
= 0.035). External ventricular drain (EVD) insertion was found to be associated with mortality (cOR 14.45, 95% CI 1.28-162.97,
= 0.031).
In this study, Filipino children underwent late time-interval of CSF diversion surgery and had mortality differences compared to their Japanese and Russian counterparts. These disparities may reflect on the functioning of the health systems of respective countries.</description><identifier>ISSN: 2296-875X</identifier><identifier>EISSN: 2296-875X</identifier><identifier>DOI: 10.3389/fsurg.2021.704346</identifier><identifier>PMID: 34513913</identifier><language>eng</language><publisher>Switzerland: Frontiers Media S.A</publisher><subject>global neurosurgery ; health systems ; Japan ; pediatric hydrocephalus ; Philippines ; Russia ; Surgery</subject><ispartof>Frontiers in surgery, 2021-08, Vol.8, p.704346-704346</ispartof><rights>Copyright © 2021 Ferraris, Palabyab, Kim, Matsumura, Yap, Cloma-Rosales, Letyagin, Muroi, Baticulon, Alcazaren, Seng and Navarro.</rights><rights>Copyright © 2021 Ferraris, Palabyab, Kim, Matsumura, Yap, Cloma-Rosales, Letyagin, Muroi, Baticulon, Alcazaren, Seng and Navarro. 2021 Ferraris, Palabyab, Kim, Matsumura, Yap, Cloma-Rosales, Letyagin, Muroi, Baticulon, Alcazaren, Seng and Navarro</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43</citedby><cites>FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428174/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428174/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34513913$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ferraris, Kevin Paul</creatorcontrib><creatorcontrib>Palabyab, Eric Paolo M</creatorcontrib><creatorcontrib>Kim, Sergei</creatorcontrib><creatorcontrib>Matsumura, Hideaki</creatorcontrib><creatorcontrib>Yap, Maria Eufemia C</creatorcontrib><creatorcontrib>Cloma-Rosales, Venus Oliva</creatorcontrib><creatorcontrib>Letyagin, German</creatorcontrib><creatorcontrib>Muroi, Ai</creatorcontrib><creatorcontrib>Baticulon, Ronnie E</creatorcontrib><creatorcontrib>Alcazaren, Jose Carlos</creatorcontrib><creatorcontrib>Seng, Kenny</creatorcontrib><creatorcontrib>Navarro, Joseph Erroll</creatorcontrib><title>Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening</title><title>Frontiers in surgery</title><addtitle>Front Surg</addtitle><description>The aim of this study is to compare specific three-institution, cross-country data that are relevant to the Global Surgery indicators and the functioning of health systems.
We retrospectively reviewed the clinical and socioeconomic characteristics of pediatric patients who underwent cerebrospinal fluid (CSF) diversion surgery for hydrocephalus in three different centers: the University of Tsukuba Hospital in Ibaraki, Japan (HIC), the Jose R. Reyes Memorial Medical Center in Manila, Philippines [low-to-middle-income country (LMIC)], and the Federal Neurosurgical Center in Novosibirsk, Russia (UMIC). The outcomes of interest were the timing of CSF diversion surgery and mortality. Statistical tests included descriptive statistics, Cox proportional hazards model, and logistic regression. Nation-level data were also obtained to provide the relevant socioeconomic contexts in discussing the results.
In total, 159 children were included, where 13 are from Japan, 99 are from the Philippines, and 47 are from the Russian Federation. The median time to surgery at the specific neurosurgical centers was 6 days in the Philippines and 1 day in both Japan and Russia. For the cohort from the Philippines, non-poor patients were more likely to receive CSF diversion surgery at an earlier time (HR = 4.74, 95% CI 2.34-9.61,
<0.001). In the same center, those with infantile or posthemorrhagic hydrocephalus (HR = 3.72, 95% CI 1.70-8.15,
= 0.001) were more likely to receive CSF diversion earlier compared to those with congenital hydrocephalus, and those with postinfectious (HR = 0.39, 95% CI 0.22-0.70,
= 0.002) or myelomeningocele-associated hydrocephalus (HR = 0.46, 95% CI 0.22-0.95,
= 0.037) were less likely to undergo surgery at an earlier time. For Russia, older patients were more likely to receive or require early CSF diversion (HR = 1.07, 95% CI 1.01-1.14,
= 0.035). External ventricular drain (EVD) insertion was found to be associated with mortality (cOR 14.45, 95% CI 1.28-162.97,
= 0.031).
In this study, Filipino children underwent late time-interval of CSF diversion surgery and had mortality differences compared to their Japanese and Russian counterparts. These disparities may reflect on the functioning of the health systems of respective countries.</description><subject>global neurosurgery</subject><subject>health systems</subject><subject>Japan</subject><subject>pediatric hydrocephalus</subject><subject>Philippines</subject><subject>Russia</subject><subject>Surgery</subject><issn>2296-875X</issn><issn>2296-875X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkk1v1DAQhiMEolXpD-CCfOSSxV_54oBUIuiuVATSgsTNcuxJ1pUTL7ZTKX-E34vTLVV7GHlkv_PMePRm2VuCN4zVzYc-zH7YUEzJpsKc8fJFdk5pU-Z1Vfx--SQ_yy5DuMUYE8ZJSfnr7IzxgrCGsPPs77V1nbRon2DgF7SbtFEyOh-QnDT6AdrI6I1C20V7p-B4kHYOH9EV-jbbaBRMETxqvQshb908xcRo3XiUXkZzB2gfZ72gz7Ox2kwDigdArQyAeufRFqSNB7RfQoQxKT1MQxJMSfgme9VLG-Dy4bzIfn398rPd5jffr3ft1U2uWFPEHApGO84rzntSSIZJictSFSmANbSolVRQNUWnpOx73fUV4V2lsdaac057zi6y3YmrnbwVR29G6RfhpBH3F84PQvr0TQuC9JSVdaOVrjlXtK4BEo7Ruux0gwEn1qcT6zh3I-h1NV7aZ9DnL5M5iMHdiZrTmlTrMO8fAN79mSFEMZqgwFo5gZuDoEVFKWEVZklKTlK1bt5D_9iGYLHaQ9zbQ6z2ECd7pJp3T-d7rPhvBvYP5Pi7Aw</recordid><startdate>20210826</startdate><enddate>20210826</enddate><creator>Ferraris, Kevin Paul</creator><creator>Palabyab, Eric Paolo M</creator><creator>Kim, Sergei</creator><creator>Matsumura, Hideaki</creator><creator>Yap, Maria Eufemia C</creator><creator>Cloma-Rosales, Venus Oliva</creator><creator>Letyagin, German</creator><creator>Muroi, Ai</creator><creator>Baticulon, Ronnie E</creator><creator>Alcazaren, Jose Carlos</creator><creator>Seng, Kenny</creator><creator>Navarro, Joseph Erroll</creator><general>Frontiers Media S.A</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20210826</creationdate><title>Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening</title><author>Ferraris, Kevin Paul ; Palabyab, Eric Paolo M ; Kim, Sergei ; Matsumura, Hideaki ; Yap, Maria Eufemia C ; Cloma-Rosales, Venus Oliva ; Letyagin, German ; Muroi, Ai ; Baticulon, Ronnie E ; Alcazaren, Jose Carlos ; Seng, Kenny ; Navarro, Joseph Erroll</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>global neurosurgery</topic><topic>health systems</topic><topic>Japan</topic><topic>pediatric hydrocephalus</topic><topic>Philippines</topic><topic>Russia</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ferraris, Kevin Paul</creatorcontrib><creatorcontrib>Palabyab, Eric Paolo M</creatorcontrib><creatorcontrib>Kim, Sergei</creatorcontrib><creatorcontrib>Matsumura, Hideaki</creatorcontrib><creatorcontrib>Yap, Maria Eufemia C</creatorcontrib><creatorcontrib>Cloma-Rosales, Venus Oliva</creatorcontrib><creatorcontrib>Letyagin, German</creatorcontrib><creatorcontrib>Muroi, Ai</creatorcontrib><creatorcontrib>Baticulon, Ronnie E</creatorcontrib><creatorcontrib>Alcazaren, Jose Carlos</creatorcontrib><creatorcontrib>Seng, Kenny</creatorcontrib><creatorcontrib>Navarro, Joseph Erroll</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Frontiers in surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferraris, Kevin Paul</au><au>Palabyab, Eric Paolo M</au><au>Kim, Sergei</au><au>Matsumura, Hideaki</au><au>Yap, Maria Eufemia C</au><au>Cloma-Rosales, Venus Oliva</au><au>Letyagin, German</au><au>Muroi, Ai</au><au>Baticulon, Ronnie E</au><au>Alcazaren, Jose Carlos</au><au>Seng, Kenny</au><au>Navarro, Joseph Erroll</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening</atitle><jtitle>Frontiers in surgery</jtitle><addtitle>Front Surg</addtitle><date>2021-08-26</date><risdate>2021</risdate><volume>8</volume><spage>704346</spage><epage>704346</epage><pages>704346-704346</pages><issn>2296-875X</issn><eissn>2296-875X</eissn><abstract>The aim of this study is to compare specific three-institution, cross-country data that are relevant to the Global Surgery indicators and the functioning of health systems.
We retrospectively reviewed the clinical and socioeconomic characteristics of pediatric patients who underwent cerebrospinal fluid (CSF) diversion surgery for hydrocephalus in three different centers: the University of Tsukuba Hospital in Ibaraki, Japan (HIC), the Jose R. Reyes Memorial Medical Center in Manila, Philippines [low-to-middle-income country (LMIC)], and the Federal Neurosurgical Center in Novosibirsk, Russia (UMIC). The outcomes of interest were the timing of CSF diversion surgery and mortality. Statistical tests included descriptive statistics, Cox proportional hazards model, and logistic regression. Nation-level data were also obtained to provide the relevant socioeconomic contexts in discussing the results.
In total, 159 children were included, where 13 are from Japan, 99 are from the Philippines, and 47 are from the Russian Federation. The median time to surgery at the specific neurosurgical centers was 6 days in the Philippines and 1 day in both Japan and Russia. For the cohort from the Philippines, non-poor patients were more likely to receive CSF diversion surgery at an earlier time (HR = 4.74, 95% CI 2.34-9.61,
<0.001). In the same center, those with infantile or posthemorrhagic hydrocephalus (HR = 3.72, 95% CI 1.70-8.15,
= 0.001) were more likely to receive CSF diversion earlier compared to those with congenital hydrocephalus, and those with postinfectious (HR = 0.39, 95% CI 0.22-0.70,
= 0.002) or myelomeningocele-associated hydrocephalus (HR = 0.46, 95% CI 0.22-0.95,
= 0.037) were less likely to undergo surgery at an earlier time. For Russia, older patients were more likely to receive or require early CSF diversion (HR = 1.07, 95% CI 1.01-1.14,
= 0.035). External ventricular drain (EVD) insertion was found to be associated with mortality (cOR 14.45, 95% CI 1.28-162.97,
= 0.031).
In this study, Filipino children underwent late time-interval of CSF diversion surgery and had mortality differences compared to their Japanese and Russian counterparts. These disparities may reflect on the functioning of the health systems of respective countries.</abstract><cop>Switzerland</cop><pub>Frontiers Media S.A</pub><pmid>34513913</pmid><doi>10.3389/fsurg.2021.704346</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2296-875X |
| ispartof | Frontiers in surgery, 2021-08, Vol.8, p.704346-704346 |
| issn | 2296-875X 2296-875X |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_1f23689dcd844c288ee7143286bd90e0 |
| source | PubMed Central |
| subjects | global neurosurgery health systems Japan pediatric hydrocephalus Philippines Russia Surgery |
| title | Global Surgery Indicators and Pediatric Hydrocephalus: A Multicenter Cross-Country Comparative Study Building the Case for Health System Strengthening |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T11%3A46%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Global%20Surgery%20Indicators%20and%20Pediatric%20Hydrocephalus:%20A%20Multicenter%20Cross-Country%20Comparative%20Study%20Building%20the%20Case%20for%20Health%20System%20Strengthening&rft.jtitle=Frontiers%20in%20surgery&rft.au=Ferraris,%20Kevin%20Paul&rft.date=2021-08-26&rft.volume=8&rft.spage=704346&rft.epage=704346&rft.pages=704346-704346&rft.issn=2296-875X&rft.eissn=2296-875X&rft_id=info:doi/10.3389/fsurg.2021.704346&rft_dat=%3Cproquest_doaj_%3E2572213703%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c395t-e532b44744f15a3016066c566ce39258cace795bcaaffdbf714b7d0ddd4442f43%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2572213703&rft_id=info:pmid/34513913&rfr_iscdi=true |