The Evolution of Pharmacological Activities Bouea macrophylla Griffith In Vivo and In Vitro Study: A Review

Griffith ( is one of the many herbal plants found in Asia, and its fruit is plum mango. This plant is rich in secondary metabolites, including flavonoids, tannins, polyphenolic compounds, and many others. Due to its bioactive components, plum mango has powerful antioxidants that have therapeutic ben...

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Published in:Pharmaceuticals (Basel, Switzerland) Switzerland), 2022-02, Vol.15 (2), p.238
Main Authors: Fu'adah, Intan Tsamrotul, Sumiwi, Sri Adi, Wilar, Gofarana
Format: Article
Language:English
Subjects:
anticancer
antihyperglycemic
antimicrobial
antioxidant
Antioxidants
antiphotoaging
Bouea macrophylla Griffith
Cancer
Carbohydrates
Diabetes
Flavonoids
Free radicals
Fruits
Glucose
Herbal medicine
Hydrocarbons
Phytochemicals
Review
Seeds
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Summary:Griffith ( is one of the many herbal plants found in Asia, and its fruit is plum mango. This plant is rich in secondary metabolites, including flavonoids, tannins, polyphenolic compounds, and many others. Due to its bioactive components, plum mango has powerful antioxidants that have therapeutic benefits for many common ailments, including cardiovascular disease, diabetes, and cancer. This review describes the evolution of plum mango's phytochemical properties and pharmacological activities including in vitro and in vivo studies. The pharmacological activities of Griffith reviewed in this article are antioxidant, anticancer, antihyperglycemic, antimicrobial, and antiphotoaging. Each of these pharmacological activities described and studied the possible cellular and molecular mechanisms of action. Interestingly, plum mango seeds show good pharmacological activity where the seed is the part of the plant that is a waste product. This can be an advantage because of its economic value as a herbal medicine. Overall, the findings described in this review aim to allow this plant to be explored and utilized more widely, especially as a new drug discovery.
ISSN:1424-8247
1424-8247
DOI:10.3390/ph15020238