Risk factors for postoperative infections in esophageal tumor patients

• Published in: Heliyon 2023-10, Vol.9 (10), p.e20741-e20741, Article e20741
• Main Authors: Lin, Mingzhu, Wang, Lu, Liu, Mengxing, Gu, Huawei, Li, Dan, Hou, Xidong, Yang, Hongye, Shi, Yu
• Format: Article
• Language: English
• Subjects: death; Esophageal cancer patients; esophageal neoplasms; Esophageal tumor surgery; hospitals; Postoperative infections; regression analysis; risk; Risk factors; surgery
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2023.e20741

Postoperative infections (PI) are a serious complication after esophageal cancer surgery, as they might be correlated with an elevated risk of death. While several reports discuss risk factors for PI in esophageal tumor surgery, there is a limited amount of research on overall postoperative infections. Therefore, investigating the factors that influence PI holds great clinical significance. We retrospectively reviewed surgical data from a cohort of 902 patients diagnosed with esophageal tumors. The study included esophageal cancer patients treated in the Department of Thoracic Surgery at Anyang Tumor Hospital from January to December 2021. Preoperative and operative risk factors for PI were evaluated using univariable and multivariable analyses. The overall incidence of PI was 28.3% (255/902). Multivariable logistic regression analysis revealed that smoking and preoperative hospital stays are significant risk factors for PI after esophageal tumor surgery. Smoking and preoperative hospital stays are identified as risk factors for PI following esophageal tumor surgery. Based on our results, we predict that certain groups of patients may have a higher risk of PI following esophageal tumor surgery. Preventive measures or closely monitor of these patients may be required to reduce the incidence of postoperative PI.