Oncogenic Brain Metazoan Parasite Infection

Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis,...

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Published in:Case reports in neurological medicine 2013-01, Vol.2013 (2013), p.1-6
Main Authors: Miller, Douglas C., Tanaka, Tomoko, Ding, Qing-Qing, Gabor, Oroszi, Spurgeon, Angela N., Cress, Marshall C.
Format: Article
Language:English
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Case Report
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Summary:Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.
ISSN:2090-6668
2090-6676
DOI:10.1155/2013/263718