ECMO support as a bridge to lung transplantation is an independent risk factor for bronchial anastomotic dehiscence

Airway complications are frequent after lung transplantation (LT), as they affect up to 23% of recipients. The implication of perioperative extracorporeal membrane oxygenation (ECMO) support and haemodynamic instability has never been specifically assessed. The first aim of this study was to explore...

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Published in:BMC pulmonary medicine 2022-12, Vol.22 (1), p.482-482, Article 482
Main Authors: Atchade, Enora, Ren, Mélissa, Jean-Baptiste, Sylvain, Tran Dinh, Alexy, Tanaka, Sébastien, Tashk, Parvine, Lortat-Jacob, Brice, Assadi, Maksud, Weisenburger, Gaelle, Mal, Hervé, Sénémaud, Jean Nicolas, Castier, Yves, de Tymowski, Christian, Montravers, Philippe
Format: Article
Language:English
Subjects:
Airway complications
Blood oxygenation, Extracorporeal
Bronchial anastomotic dehiscence
Dehiscence
Extra corporeal membrane oxygenation
Extracorporeal Membrane Oxygenation - adverse effects
Humans
Life Sciences
Lung transplantation
Lung Transplantation - adverse effects
Lungs
Patient outcomes
Prevention
Retrospective Studies
Risk Factors
Septic shock
Transplantation
Treatment Outcome
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Summary:Airway complications are frequent after lung transplantation (LT), as they affect up to 23% of recipients. The implication of perioperative extracorporeal membrane oxygenation (ECMO) support and haemodynamic instability has never been specifically assessed. The first aim of this study was to explore the impact of perioperative ECMO support on bronchial anastomotic dehiscence (BAD) at Day 90 after LT. This prospective observational monocentric study analysed BAD in all consecutive patients who underwent LT in the Bichat Claude Bernard Hospital, Paris, France, between January 2016 and May 2019. BAD visible on bronchial endoscopy and/or tomodensitometry was recorded. A univariate analysis was performed (Fisher's exacts and Mann-Whitney tests), followed by a multivariate analysis to assess independent risk factors for BAD during the first 90 days after LT (p 
ISSN:1471-2466
1471-2466
DOI:10.1186/s12890-022-02280-9