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Comparative Genomics of Prunus -Associated Members of the Pseudomonas syringae Species Complex Reveals Traits Supporting Co-evolution and Host Adaptation
Members of the species complex cause symptoms that are ranging from leaf spots to cankers on a multitude of plant species, including some of the genus . To date, a total of two species of the species complex and six different pathovars have been associated with diseases on spp., which were shown to...
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| Published in: | Frontiers in microbiology 2022-05, Vol.13, p.804681-804681 |
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| container_title | Frontiers in microbiology |
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| creator | Ruinelli, Michela Blom, Jochen Smits, Theo H M Pothier, Joël F |
| description | Members of the
species complex cause symptoms that are ranging from leaf spots to cankers on a multitude of plant species, including some of the genus
. To date, a total of two species of the
species complex and six different pathovars have been associated with diseases on
spp., which were shown to belong to different phylogenetic units (phylogroups, PG) based on sequence similarity of housekeeping genes or whole genomes, suggesting that virulence to
spp. may be the result of convergent pathoadaptation. In this study, a comparative genomics approach was used to determine genes significantly associated with strains isolated from
spp. across a phylogeny of 97 strains belonging to the
species complex. Our study revealed the presence of a set of orthologous proteins which were significantly associated with strains isolated from
spp. than in strains isolated from other hosts or from non-agricultural environments. Among them, the type III effector HopAY predicted to encode for a C58 cysteine protease was found to be highly associated with strains isolated from
spp. and revealed patterns supporting co-evolution and host adaptation. |
| doi_str_mv | 10.3389/fmicb.2022.804681 |
| format | article |
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species complex cause symptoms that are ranging from leaf spots to cankers on a multitude of plant species, including some of the genus
. To date, a total of two species of the
species complex and six different pathovars have been associated with diseases on
spp., which were shown to belong to different phylogenetic units (phylogroups, PG) based on sequence similarity of housekeeping genes or whole genomes, suggesting that virulence to
spp. may be the result of convergent pathoadaptation. In this study, a comparative genomics approach was used to determine genes significantly associated with strains isolated from
spp. across a phylogeny of 97 strains belonging to the
species complex. Our study revealed the presence of a set of orthologous proteins which were significantly associated with strains isolated from
spp. than in strains isolated from other hosts or from non-agricultural environments. Among them, the type III effector HopAY predicted to encode for a C58 cysteine protease was found to be highly associated with strains isolated from
spp. and revealed patterns supporting co-evolution and host adaptation.</description><identifier>ISSN: 1664-302X</identifier><identifier>EISSN: 1664-302X</identifier><identifier>DOI: 10.3389/fmicb.2022.804681</identifier><identifier>PMID: 35592008</identifier><language>eng</language><publisher>Switzerland: Frontiers Media S.A</publisher><subject>co-evolution ; comparative genomics ; host adaptation ; Microbiology ; pathogenicity ; Pseudomonas syringae species complex</subject><ispartof>Frontiers in microbiology, 2022-05, Vol.13, p.804681-804681</ispartof><rights>Copyright © 2022 Ruinelli, Blom, Smits and Pothier.</rights><rights>Copyright © 2022 Ruinelli, Blom, Smits and Pothier. 2022 Ruinelli, Blom, Smits and Pothier</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c417t-debddc827864572efce65ab9a462da47d9efbacff566a1db98cdd094b47f011e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111521/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111521/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35592008$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ruinelli, Michela</creatorcontrib><creatorcontrib>Blom, Jochen</creatorcontrib><creatorcontrib>Smits, Theo H M</creatorcontrib><creatorcontrib>Pothier, Joël F</creatorcontrib><title>Comparative Genomics of Prunus -Associated Members of the Pseudomonas syringae Species Complex Reveals Traits Supporting Co-evolution and Host Adaptation</title><title>Frontiers in microbiology</title><addtitle>Front Microbiol</addtitle><description>Members of the
species complex cause symptoms that are ranging from leaf spots to cankers on a multitude of plant species, including some of the genus
. To date, a total of two species of the
species complex and six different pathovars have been associated with diseases on
spp., which were shown to belong to different phylogenetic units (phylogroups, PG) based on sequence similarity of housekeeping genes or whole genomes, suggesting that virulence to
spp. may be the result of convergent pathoadaptation. In this study, a comparative genomics approach was used to determine genes significantly associated with strains isolated from
spp. across a phylogeny of 97 strains belonging to the
species complex. Our study revealed the presence of a set of orthologous proteins which were significantly associated with strains isolated from
spp. than in strains isolated from other hosts or from non-agricultural environments. Among them, the type III effector HopAY predicted to encode for a C58 cysteine protease was found to be highly associated with strains isolated from
spp. and revealed patterns supporting co-evolution and host adaptation.</description><subject>co-evolution</subject><subject>comparative genomics</subject><subject>host adaptation</subject><subject>Microbiology</subject><subject>pathogenicity</subject><subject>Pseudomonas syringae species complex</subject><issn>1664-302X</issn><issn>1664-302X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVksFu3CAQhq2qVROleYBeKo69OAWMAV8qrVZtEilVoyaVekMYhg2RbVzAq-ZR-rZld9Mo4QCjmX--GYm_qt4TfNY0svvkRm_6M4opPZOYcUleVceEc1Y3mP56_Sw-qk5TusflMEzL_bY6atq2K6E8rv6uwzjrqLPfAjqHKRRqQsGh67hMS0L1KqVgvM5g0TcYe4j7ar4DdJ1gsWEMk04oPUQ_bTSgmxmMh4R22AH-oB-wBT0kdBu1zwndLPMcYi7aoqhhG4Yl-zAhPVl0EVJGK6vnrHe5d9UbVzrh9PE9qX5-_XK7vqivvp9frldXtWFE5NpCb62RVEjOWkHBGeCt7jvNOLWaCduB67VxruVcE9t30liLO9Yz4TAh0JxUlweuDfpezdGPOj6ooL3aJ0LcKF02NgMoijkTvSS66TkDITvLnGwlsQ5T1ghRWJ8PrHnpR7AGphz18AL6sjL5O7UJW9URQlpKCuDjIyCG3wukrEafDAyDniAsSVHOhZBt-coiJQepiSGlCO5pDMFq5xC1d4jaOUQdHFJ6Pjzf76njvx-afzCAvLA</recordid><startdate>20220503</startdate><enddate>20220503</enddate><creator>Ruinelli, Michela</creator><creator>Blom, Jochen</creator><creator>Smits, Theo H M</creator><creator>Pothier, Joël F</creator><general>Frontiers Media S.A</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20220503</creationdate><title>Comparative Genomics of Prunus -Associated Members of the Pseudomonas syringae Species Complex Reveals Traits Supporting Co-evolution and Host Adaptation</title><author>Ruinelli, Michela ; Blom, Jochen ; Smits, Theo H M ; Pothier, Joël F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-debddc827864572efce65ab9a462da47d9efbacff566a1db98cdd094b47f011e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>co-evolution</topic><topic>comparative genomics</topic><topic>host adaptation</topic><topic>Microbiology</topic><topic>pathogenicity</topic><topic>Pseudomonas syringae species complex</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ruinelli, Michela</creatorcontrib><creatorcontrib>Blom, Jochen</creatorcontrib><creatorcontrib>Smits, Theo H M</creatorcontrib><creatorcontrib>Pothier, Joël F</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Frontiers in microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ruinelli, Michela</au><au>Blom, Jochen</au><au>Smits, Theo H M</au><au>Pothier, Joël F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Genomics of Prunus -Associated Members of the Pseudomonas syringae Species Complex Reveals Traits Supporting Co-evolution and Host Adaptation</atitle><jtitle>Frontiers in microbiology</jtitle><addtitle>Front Microbiol</addtitle><date>2022-05-03</date><risdate>2022</risdate><volume>13</volume><spage>804681</spage><epage>804681</epage><pages>804681-804681</pages><issn>1664-302X</issn><eissn>1664-302X</eissn><abstract>Members of the
species complex cause symptoms that are ranging from leaf spots to cankers on a multitude of plant species, including some of the genus
. To date, a total of two species of the
species complex and six different pathovars have been associated with diseases on
spp., which were shown to belong to different phylogenetic units (phylogroups, PG) based on sequence similarity of housekeeping genes or whole genomes, suggesting that virulence to
spp. may be the result of convergent pathoadaptation. In this study, a comparative genomics approach was used to determine genes significantly associated with strains isolated from
spp. across a phylogeny of 97 strains belonging to the
species complex. Our study revealed the presence of a set of orthologous proteins which were significantly associated with strains isolated from
spp. than in strains isolated from other hosts or from non-agricultural environments. Among them, the type III effector HopAY predicted to encode for a C58 cysteine protease was found to be highly associated with strains isolated from
spp. and revealed patterns supporting co-evolution and host adaptation.</abstract><cop>Switzerland</cop><pub>Frontiers Media S.A</pub><pmid>35592008</pmid><doi>10.3389/fmicb.2022.804681</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | Open Access: PubMed Central |
| subjects | co-evolution comparative genomics host adaptation Microbiology pathogenicity Pseudomonas syringae species complex |
| title | Comparative Genomics of Prunus -Associated Members of the Pseudomonas syringae Species Complex Reveals Traits Supporting Co-evolution and Host Adaptation |
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