Depression, Olfaction, and Quality of Life: A Mutual Relationship

Olfactory dysfunction has been well studied in depression. Common brain areas are involved in depression and in the olfactory process, suggesting that olfactory impairments may constitute potential markers of this disorder. Olfactory markers of depression can be either state (present only in symptom...

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Bibliographic Details
Published in:Brain sciences 2018-05, Vol.8 (5), p.80
Main Authors: Rochet, Marion, El-Hage, Wissam, Richa, Sami, Kazour, François, Atanasova, Boriana
Format: Article
Language:English
Subjects:
depression
Etiology
Human health and pathology
Information processing
Life Sciences
Literature reviews
markers
Mental depression
Olfaction
Psychiatrics and mental health
Quality of life
Remission
Review
therapeutic tool
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Summary:Olfactory dysfunction has been well studied in depression. Common brain areas are involved in depression and in the olfactory process, suggesting that olfactory impairments may constitute potential markers of this disorder. Olfactory markers of depression can be either state (present only in symptomatic phases) or trait (persistent after symptomatic remission) markers. This study presents the etiology of depression, the anatomical links between olfaction and depression, and a literature review of different olfactory markers of depression. Several studies have also shown that olfactory impairment affects the quality of life and that olfactory disorders can affect daily life and may be lead to depression. Thus, this study discusses the links between olfactory processing, depression, and quality of life. Finally, olfaction is an innovative research field that may constitute a new therapeutic tool for the treatment of depression.
ISSN:2076-3425
2076-3425
DOI:10.3390/brainsci8050080