Elucidating the intricacies of the H2S signaling pathway in gasotransmitters: Highlighting the regulation of plant thiocyanate detoxification pathways

• Published in: Ecotoxicology and environmental safety 2024-05, Vol.276, p.116307-116307, Article 116307
• Main Authors: Feng, Yu-Xi, Tian, Peng, Li, Cheng-Zhi, Hu, Xiao-Dong, Lin, Yu-Juan
• Format: Article
• Language: English
• Subjects: Assimilation; Hydrogen sulfide; Signaling molecule; Thiocyanate; Uptake and toxicity
• ISSN: 0147-6513; 1090-2414
• DOI: 10.1016/j.ecoenv.2024.116307

In recent decades, there has been increasing interest in elucidating the role of sulfur-containing compounds in plant metabolism, particularly emphasizing their function as signaling molecules. Among these, thiocyanate (SCN−), a compound imbued with sulfur and nitrogen, has emerged as a significant environmental contaminant frequently detected in irrigation water. This compound is known for its potential to adversely impact plant growth and agricultural yield. Although adopting exogenous SCN− as a nitrogen source in plant cells has been the subject of thorough investigation, the fate of sulfur resulting from the assimilation of exogenous SCN− has not been fully explored. There is burgeoning curiosity in probing the fate of SCN− within plant systems, especially considering the possible generation of the gaseous signaling molecule, hydrogen sulfide (H2S) during the metabolism of SCN−. Notably, the endogenous synthesis of H2S occurs predominantly within chloroplasts, the cytosol, and mitochondria. In contrast, the production of H2S following the assimilation of exogenous SCN− is explicitly confined to chloroplasts and mitochondria. This phenomenon indicates complex interplay and communication among various subcellular organelles, influencing signal transduction and other vital physiological processes. This review, augmented by a small-scale experimental study, endeavors to provide insights into the functional characteristics of H2S signaling in plants subjected to SCN−-stress. Furthermore, a comparative analysis of the occurrence and trajectory of endogenous H2S and H2S derived from SCN−-assimilation within plant organisms was performed, providing a focused lens for a comprehensive examination of the multifaceted roles of H2S in rice plants. By delving into these dimensions, our objective is to enhance the understanding of the regulatory mechanisms employed by the gasotransmitter H2S in plant adaptations and responses to SCN−-stress, yielding invaluable insights into strategies for plant resilience and adaptive capabilities. [Display omitted] •Fate of hydrogen sulfide (H2S) derived from thiocyanate (SCN−) assimilation in plant was assessed.•The concept of SCN− as innate H2S flux in plant cells was first proposed.•Crosstalk between endogenous H2S and H2S derived from SCN− assimilation was analysed•The promotive roles of H2S in plant under SCN− stress were summarized.