Abruptio Placentae Caused by Hypertriglyceridemia-Induced Acute Pancreatitis during Pregnancy: Case Report and Literature Review

Background. Hormonal effects during pregnancy can compromise otherwise controlled lipid levels in women with hypertriglyceridemia and predispose to pancreatitis leading to increased morbidity for mother and fetus. Elevation of triglyceride levels is a risk factor for development of pancreatitis if i...

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Bibliographic Details
Published in:Case reports in obstetrics and gynecology 2018, Vol.2018 (2018), p.1-8
Main Authors: Yalcin Bahat, Pınar, Aslan Cetin, Berna, Turan, Gokce
Format: Article
Language:English
Subjects:
Abdomen
Abruptio placentae
Alcohol
Anticoagulants
Blood
Case Report
Case reports
Cesarean section
Diabetes
Gallstones
Gastroenterology
Gynecology
Health aspects
Hyperlipidemia
Insulin
Lipids
Lipoproteins
Literature reviews
Maternal mortality
Medical examination
Medical imaging
Medical treatment
Metabolism
Obstetrics
Pain
Pancreatitis
Patients
Physiology
Placenta
Pregnancy
Pregnant women
Triglycerides
Ultrasonic imaging
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Summary:Background. Hormonal effects during pregnancy can compromise otherwise controlled lipid levels in women with hypertriglyceridemia and predispose to pancreatitis leading to increased morbidity for mother and fetus. Elevation of triglyceride levels is a risk factor for development of pancreatitis if it exceeds 1000 mg/dL. Pancreatitis should be considered in emergency cases of abdominal pain and uterine contractions in Emergency Department at any stage of pregnancy. We report a case of abruptio placentae caused by hypertriglyceridemia-induced acute pancreatitis. Also, literature review of cases of acute pancreatitis induced by hypertriglycaemia in pregnancy has been made. Case. A 22-year-old woman presented to our Emergency Department, at 35 weeks of gestation, for acute onset of abdominal pain and uterine contractions. Blood tests showed a high rate of triglyceride. The patient was diagnosed with abruptio placentae caused by hypertriglyceridemia-induced acute pancreatitis. Immediate cesarean section was performed and it was observed that blood sample revealed a milky turbid serum. Insulin, heparin, and supportive treatment were started. She was discharged on the 10th day. Conclusion. Consequently, patients with known hypertriglyceridemia or family history should be followed up more closely because any delay can cause disastrous conclusions for mother and fetus. Acute pancreatitis should be considered in pregnant women who have sudden onset, severe, persistent epigastric pain and who have a risk factor for acute pancreatitis.
ISSN:2090-6684
2090-6692
DOI:10.1155/2018/3869695