Does nanobiotechnology create new tools to combat microorganisms?

Antimicrobial resistance is still a crucial global problem related to the overuse of antibiotics and natural microorganism capability for rapid horizontal evolution. Even new generations of drugs are not able to overcome bacterial defence mechanisms. A novel solution for this immense medical challen...

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Bibliographic Details
Published in:Nanotechnology reviews (Berlin) 2017-04, Vol.6 (2), p.171-189
Main Authors: Zielińska-Górska, Marlena K., Sawosz, Ewa, Górski, Konrad, Chwalibog, André
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial activity
Antimicrobial agents
Antimicrobial resistance
Bacteriology
drug delivery
Microorganisms
nanobiotechnology
Nanomaterials
nanoparticles
Nanotechnology
nanotoxicity
Physicochemical properties
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Summary:Antimicrobial resistance is still a crucial global problem related to the overuse of antibiotics and natural microorganism capability for rapid horizontal evolution. Even new generations of drugs are not able to overcome bacterial defence mechanisms. A novel solution for this immense medical challenge can be nanomaterials. Researchers indicate that modern nanoforms can effectively support and perhaps in the long-term replace traditional bactericidal agents. Because of their unique physicochemical properties, nanotechnology products can exert multiple actions against bacteria, which might be efficient against even multidrug-resistant pathogens. In this review, we discuss the documented achievements and concerns associated with broad potential applications of nanoforms in the fight against microorganisms.
ISSN:2191-9089
2191-9097
DOI:10.1515/ntrev-2016-0042