The clinical relevance of quality of life in heart failure patients with preserved ejection fraction

Aims Patient reported outcomes (PROs) are gradually being incorporated into daily practice to assess individual health‐related quality of life (QOL). However, despite accumulating evidence of the prognostic utility of heart failure (HF)‐specific QOL indices, evidence on the generic QOL score is scar...

Full description

Saved in:
Bibliographic Details
Published in:ESC Heart Failure 2023-04, Vol.10 (2), p.995-1002
Main Authors: Seo, Masahiro, Watanabe, Tetsuya, Yamada, Takahisa, Yano, Masamichi, Hayashi, Takaharu, Nakagawa, Akito, Nakagawa, Yusuke, Tamaki, Shunsuke, Yasumura, Yoshio, Sotomi, Yohei, Hikoso, Shungo, Nakatani, Daisaku, Fukunami, Masatake, Sakata, Yasushi
Format: Article
Language:English
Subjects:
Activities of daily living
Body mass index
Chronic fatigue syndrome
Clinical outcomes
Clinical Relevance
Data collection
Diabetes
Ejection fraction
EQ‐5D
Frailty
Heart Failure
Hemoglobin
HFpEF
Humans
Hypertension
Laboratories
Morbidity
Mortality
Observational studies
Original
Patients
Peptides
Prospective Studies
Quality of Life
Questionnaires
Software
Stroke Volume
Surveys and Questionnaires
Trends
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aims Patient reported outcomes (PROs) are gradually being incorporated into daily practice to assess individual health‐related quality of life (QOL). However, despite accumulating evidence of the prognostic utility of heart failure (HF)‐specific QOL indices, evidence on the generic QOL score is scarce, especially in patients with HF with preserved ejection fraction (HFpEF). Methods and results Patient data were extracted from the Prospective mUlticenteR obServational stUdy of patIenTs with Heart Failure with Preserved Ejection Fraction (PURSUIT HFpEF) study. EuroQol 5 dimensions 5‐level (EQ‐5D‐5L) data were obtained at discharge to evaluate patients' health‐related QOL. The study population (n = 864) was divided into tertiles based on their EQ‐5D‐5L index as follows: low EQ‐5D‐5L 0.038–0.664 (n = 287), middle EQ‐5D‐5L 0.665–0.867 (n = 293), and high EQ‐5D‐5L 0.871–1.000 (n = 284). A total of 206 patients died over a mean follow‐up period of 2.0 ± 1.2 years. Kaplan–Meier analysis revealed that the risk of mortality increased with the tertile of the EQ‐5D‐5L index (34% vs. 23% vs. 14%, P 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.14270