Approximating dementia prevalence in population‐based surveys of aging worldwide: An unsupervised machine learning approach

Introduction Ability to determine dementia prevalence in low‐ and middle‐income countries (LMIC) remains challenging because of frequent lack of data and large discrepancies in dementia case ascertainment. Methods High likelihood of dementia was determined with hierarchical clustering after principa...

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Bibliographic Details
Published in:Alzheimer's & dementia : translational research & clinical interventions 2020, Vol.6 (1), p.e12074-n/a
Main Authors: Cleret de Langavant, Laurent, Bayen, Eléonore, Bachoud‐Lévi, Anne‐Catherine, Yaffe, Kristine
Format: Article
Language:English
Subjects:
Activities of daily living
Age
Aging
Alzheimer's disease
Classification
Cognition & reasoning
Dementia
Demographics
Education
Human health and pathology
Life Sciences
Longitudinal studies
Low income groups
low‐ and middle‐income countries
Machine learning
Medical records
Polls & surveys
Population
population survey
prevalence
Sensitivity analysis
Variables
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Summary:Introduction Ability to determine dementia prevalence in low‐ and middle‐income countries (LMIC) remains challenging because of frequent lack of data and large discrepancies in dementia case ascertainment. Methods High likelihood of dementia was determined with hierarchical clustering after principal component analysis applied in 10 population surveys of aging: HRS (USA, 2014), SHARE (Europe and Israel, 2015), MHAS (Mexico, 2015), ELSI (Brazil, 2016), CHARLS (China, 2015), IFLS (Indonesia, 2014–2015), LASI (India, 2016), SAGE‐Ghana (2007), SAGE‐South Africa (2007), SAGE‐Russia (2007–2010). We approximated dementia prevalence using weighting methods. Results Estimated numbers of dementia cases were: China, 40.2 million; India, 18.0 million; Russia, 5.2 million; Europe and Israel, 5.0 million; United States, 4.4 million; Brazil, 2.2 million; Mexico, 1.6 million; Indonesia, 1.3 million; South Africa, 1.0 million; Ghana, 319,000. Discussion Our estimations were similar to prior ones in high‐income countries but much higher in LMIC. Extrapolating these results globally, we suggest that almost 130 million people worldwide were living with dementia in 2015.
ISSN:2352-8737
2352-8737
DOI:10.1002/trc2.12074