Virilizing ovarian Leydig cell tumour

Leydig cell tumours belong to the small group of ovarian steroid tumors, which are hormone producing and derived from specific stromal cells. Morphologically, their endocrine-like structure is characteristic, formed of large, polyhedral cells resembling luteal, adrenocortical and Leydig cells. They...

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Bibliographic Details
Published in:Journal of Clinical and Scientific Research 2013-04, Vol.2 (2), p.101-104
Main Authors: KV, Murali Mohan, V, Shanthi, BA, Rama Krishna, P, Niroopama, M, Anitha
Format: Article
Language:English
Subjects:
Leydig cell tumour
Reinke's crystalloids
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Summary:Leydig cell tumours belong to the small group of ovarian steroid tumors, which are hormone producing and derived from specific stromal cells. Morphologically, their endocrine-like structure is characteristic, formed of large, polyhedral cells resembling luteal, adrenocortical and Leydig cells. They contain crystalloids of Reinke in their cytoplasm which have diagnostic significance. Patients with these tumours present with androgenic manifestations. We report the occurrence of Leydig cell tumour in a 35-year-old lady who presented with infertility and hirsutism.
ISSN:2277-5706
2277-8357
DOI:10.15380/2277-5706.JCSR.12.063