Chinese Visceral Adiposity Index Is More Closely Associated With Hypertension and Prehypertension Than Traditional Adiposity Indices in Chinese Population: Results From the REACTION Study

• Published in: Frontiers in endocrinology (Lausanne) 2022-06, Vol.13, p.921997-921997
• Main Authors: Li, Binqi, Wang, Jie, Zhou, Xin, Liu, Yang, Wang, Weiqing, Gao, Zhengnan, Tang, Xulei, Yan, Li, Wan, Qin, Luo, Zuojie, Qin, Guijun, Chen, Lulu, Ning, Guang, Mu, Yiming
• Format: Article
• Language: English
• Subjects: Chinese visceral adiposity index; Endocrinology; hypertension; obesity; prehypertension; visceral adiposity; visceral adiposity index
• ISSN: 1664-2392; 1664-2392
• DOI: 10.3389/fendo.2022.921997

PurposeThe optimal adiposity index that is strongly associated with hypertension or prehypertension remains inconclusive in Chinese population. This study aimed to investigate the relationship between Chinese visceral adiposity index (CVAI) and hypertension and prehypertension, as well as to compare the discriminative power of CVAI, visceral adiposity index (VAI), body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR), low-density lipoprotein cholesterol (LDL-C), and waist-to-hip ratio (WHR) with hypertension and prehypertension in Chinese general population. Patients and MethodsA total of 34732 participants from REACTION study were recruited. Multiple logistic regression analyses were performed to detect the association between adiposity indices (CVAI, VAI, BMI, WC, WHtR, WHR, LDL-C) and hypertension and prehypertension. ResultsMultivariate logistic regression analysis showed that compared with other obesity indices, CVAI remained significantly associated with hypertension and prehypertension (Hypertension: odds ratio (OR) 3.475, 95% confidence interval (CI) 3.158-3.824, p