Detection of hepatitis A viral genome in stool samples of patients with relapsed hepatitis A by the polymerase chain reaction

Hepatitis A is a disease usually resolved in a few weeks. However, there have been reports of relapse, characterized by both clinical and biochemical means. Recently, one group reported the presence of the HAV virus in 7 cases of relapsed Hepatitis A by molecular hybridization, whereas other authors...

Full description

Saved in:
Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 1989-09, Vol.84 (3), p.429-429
Main Authors: Tedeschi, M V, Yoshida, C F, Silva, M, Feinstone, S M
Format: Article
Language:English
Subjects:
Antigens, Viral - analysis
Feces
Genome, Viral
Hepatitis A - immunology
Hepatovirus - genetics
Hepatovirus - immunology
Humans
PARASITOLOGY
Polymerase Chain Reaction
Recurrence
TROPICAL MEDICINE
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hepatitis A is a disease usually resolved in a few weeks. However, there have been reports of relapse, characterized by both clinical and biochemical means. Recently, one group reported the presence of the HAV virus in 7 cases of relapsed Hepatitis A by molecular hybridization, whereas other authors obtained negative results with this same method. The authors show the presence of the HAV genome in the stools of two out of three patients clinically diagnosed as relapsed Hepatitis A, through the amplification of a segment of the viral genome by the polymerase chain reaction (PCR).
ISSN:0074-0276
1678-8060
0074-0276
1678-8060
DOI:10.1590/S0074-02761989000300022