Antibacterial Effect of Spanish Honeys of Different Botanical Origins against Staphylococcus epidermidis

Honey is traditionally used for its medicinal properties attributed to its antibacterial and antioxidant effects. It is considered a natural alternative to conventional antibiotics. This effect has been attributed to their physico-chemical properties, as various chemical parameters can synergistical...

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Bibliographic Details
Published in:International journal of molecular sciences 2024-06, Vol.25 (12), p.6590
Main Authors: Núñez-Gómez, Vanesa, San Mateo, Marta, Sánchez-Martínez, Lorena, Periago, María Jesús
Format: Article
Language:English
Subjects:
(poly)phenol
Acids
Anti-Bacterial Agents - pharmacology
antibacterial
antioxidant
Antioxidants
Antioxidants - pharmacology
Bacterial infections
Bees
Biofilms
botanical origin
Citrus
Citrus fruits
colour
Flavonoids
Fructose
Glucose
Health aspects
Honey
Honey - analysis
Honeybee
Infections
Medical research
Medicine, Experimental
Methicillin
Microbial Sensitivity Tests
Moisture content
Phenols
Proteins
Spain
Staphylococcus epidermidis - drug effects
Wound healing
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Summary:Honey is traditionally used for its medicinal properties attributed to its antibacterial and antioxidant effects. It is considered a natural alternative to conventional antibiotics. This effect has been attributed to their physico-chemical properties, as various chemical parameters can synergistically influence this effect. The aim of this study is to assess Spanish honeys of diverse botanical origins for their antibacterial efficacy against , correlating their physico-chemical attributes, (poly)phenol content, and antioxidant activity. The methods included colour determination via two methodologies, acidity, pH, moisture content, and sugar concentration. (Poly)phenol content was quantified using the Folin-Ciocalteau method, while antioxidant activity was evaluated via the FRAP method. Subsequently, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against were investigated with different concentrations of honeys. The results revealed a direct relationship between honey darkness, (poly)phenol concentration, antioxidant activity, and antibacterial efficacy. Darker honeys exhibited higher (poly)phenol levels, greater antioxidant activity, and consequently, lower MIC and MBC values, showing enhanced antibacterial properties. These findings underscore the potential of honey as a therapeutic agent against , particularly in wound healing applications to avoid infection. Further research into honey's multifaceted properties is warranted to unveil novel therapeutic avenues in healthcare.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms25126590