A lung cancer patient with deep vein thrombosis:a case report and literature review

Venous thromboembolism (VTE) is a common problem in cancer patients and the incidence is increasing, especially for patients with lung cancer. Common features of these patients, like advanced stage, male gender, old age and chemotherapy, are risk factors of VTE. Here we reported a case in which the...

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Bibliographic Details
Published in:BMC cancer 2019-03, Vol.19 (1), p.285-285, Article 285
Main Authors: Chen, Yungu, Tsang, Yiu Sing, Chou, Xiaoxia, Hu, Jiong, Xia, Qing
Format: Article
Language:English
Subjects:
Amputation
Anticoagulants
Anticoagulants - administration & dosage
Anticoagulants - therapeutic use
Antigens
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Aspirin
Biomarkers
Biopsy
Cancer metastasis
Cancer patients
Cancer therapies
Care and treatment
Case Report
Case reports
Chemotherapy
Cisplatin - administration & dosage
Cisplatin - adverse effects
Clinical medicine
Complications and side effects
Compression therapy
Deep venous thrombosis
Development and progression
Health risk assessment
Heparin
Humans
Literature reviews
Low molecular weight heparin
Lung cancer
Lung Neoplasms - drug therapy
Lymphatic system
Male
Metastases
Metastasis
Middle Aged
Molecular weight
Mortality
Paclitaxel - administration & dosage
Paclitaxel - adverse effects
Pain
Patients
Physicians
Prevention
Prognosis
Risk factors
Smoking
Thromboembolism
Thrombolysis
Thrombophlebitis
Thrombosis
Treatment Failure
Ultrasonic imaging
Veins & arteries
Venous thrombosis
Venous Thrombosis - chemically induced
Venous Thrombosis - drug therapy
Warfarin
Warfarin - administration & dosage
Warfarin - therapeutic use
Zoledronic acid
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Description
Summary:Venous thromboembolism (VTE) is a common problem in cancer patients and the incidence is increasing, especially for patients with lung cancer. Common features of these patients, like advanced stage, male gender, old age and chemotherapy, are risk factors of VTE. Here we reported a case in which the patient with lung cancer developed deep vein thrombosis (DVT) when receiving chemotherapy. A 53-year-old male who was diagnosed with lung cancer with multiple metastasis developed severe DVT during chemotherapy. Despite the use of aspirin, warfarin and low molecular weight heparin (LMWH) for anticoagulant and thrombolytic therapy, the condition was still deteriorating, resulting in amputation finally. It's rare that the conditions of cancer patients who develop venous thromboembolism (VTE) keep deteriorating despite the administration of aspirin, warfarin and low weight molecular heparin. Both early diagnosis and prophylactic use of anticoagulants are suggested for cancer patients to improve the prognosis.
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-019-5513-8