Feasibility analysis of flexible bronchoscopy in conjunction with noninvasive ventilation for therapy of hypoxemic patients with Central Airway Obstruction: a retrospective study

Interventional bronchoscopy for hypoxemic patients with central airway obstruction (CAO) is typically performed under general anesthesia. This approach poses remarkable challenge for both bronchoscopist and anesthesiologist. Noninvasive ventilation (NIV) during flexible bronchoscopy (FB) has been su...

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Bibliographic Details
Published in:PeerJ (San Francisco, CA) CA), 2020-04, Vol.8, p.e8687-e8687, Article e8687
Main Authors: Chen, Xiaoke, Zhou, Yiping, Yu, Haiqiong, Peng, Yue, Xia, Liping, Liu, Nian, Lin, Hairong
Format: Article
Language:English
Subjects:
Airway management
Airway obstruction
Analysis
Anesthesia
Blood pressure
Bronchoscopy
Cardiovascular disease
Care and treatment
Dezocine
Drugs and Devices
Emergency and Critical Care
Health aspects
Heart rate
Hospitals
Hypertension
Oxygenation
Patients
Respiratory Medicine
Respiratory tract
Software
Statistical analysis
Time
Tuberculosis
Ventilation
Ventilators
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Summary:Interventional bronchoscopy for hypoxemic patients with central airway obstruction (CAO) is typically performed under general anesthesia. This approach poses remarkable challenge for both bronchoscopist and anesthesiologist. Noninvasive ventilation (NIV) during flexible bronchoscopy (FB) has been successfully used in hypoxemic patients, but rarely in the treatment of hypoxemic patients with CAO. To evaluate the feasibility of therapeutic FB assisted with NIV for therapy of hypoxemic patients with CAO. Twenty-nine hypoxemic CAO patients treated with FB from December 2010 to May 2016 in our hospital were retrospectively reviewed, either aided with NIV under sedation (NIV group ) or through artificial airway under general anesthesia (control group). Interventional procedures included balloon dilation, electrocautery and argon plasma coagulation. Fifteen patients were enrolled in the NIV group and 14 in the control group. The success rate (93.3% VS 92.9%,  = 1.0), procedure time (60.5 ± 4.2 min VS 67.8 ± 5.6 min,  = 0.31) and oxygenation improvement between the two groups have no significant difference. Less reduction of systolic blood pressure and heart rate during procedure was observed in the NIV group. The NIV group showed shorter admission time before procedure than the control group (35.1 ± 4.6 h VS 55.6 ± 5.6 h,  
ISSN:2167-8359
2167-8359
DOI:10.7717/peerj.8687