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Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach

Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A...

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Published in:	Balneo and PRM Research Journal (Online. English ed.) 2025-12, Vol.15 (4), p.756
Main Authors:	Oana Raluca Antonescu, Sinziana Calina Silisteanu, Alina Cristiana Venter, Mihaela Racheriu, Irina Elena Antonescu, Enikő Nemes-Nagy
Format:	Article
Language:	English
Subjects:	biomarkers osteoporosis postmenopausal women screening
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container_title	Balneo and PRM Research Journal (Online. English ed.)
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creator	Oana Raluca Antonescu Sinziana Calina Silisteanu Alina Cristiana Venter Mihaela Racheriu Irina Elena Antonescu Enikő Nemes-Nagy
description	Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A retrospective study was conducted, which included an initial cohort of 243 patients hospitalized between January 2023 and December 2023 at the County Emergency Hospital of Sibiu, Clinical Endocrinology Department ; Study results suggest that assessment of bone mineral density (BMD) remains a primary standard in the diagnosis of osteoporosis, as measured by T and Z scores from DXA densitometry. However, biomarkers such as total calcium, ionic calcium, vitamin D, phosphorus, PTH and bone degradation markers (e.g. Beta Crosslaps) play a significant role in assessing bone metabolism and identifying fracture risk; The study highlights the importance of screening in postmenopausal women and the need for calcium and vitamin D supplementation in patients with osteoporosis or osteopenia
doi_str_mv	10.12680/balneo.2024.756
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subjects	biomarkers osteoporosis postmenopausal women screening
title	Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach
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