Concomitant clear cell renal cell carcinoma with osseous metaplasia and papillary thyroid microcarcinoma: a case report with literature review

Backgrounds Although calcifications have been observed in various renal masses, osseous metaplasia has very rarely been reported. Here, we present a case of concomitant clear cell renal cell carcinoma with osseous metaplasia and papillary thyroid microcarcinoma. Case presentation A 52-year-old male...

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Bibliographic Details
Published in:African journal of urology 2023-12, Vol.29 (1), p.20-5, Article 20
Main Authors: Fakhralddin, Saman S., Qader, Deedar K., Salih, Abdulwahid M., Abdullah, Ari M., Baba, Hiwa O., Tahir, Soran H., Qaradakhy, Aras J., Hiwa, Dilan S., Kakamad, Fahmi H.
Format: Article
Language:English
Subjects:
Abdomen
Adipocytes
Appendectomy
Bone islands
Bone marrow
Calcification
Carcinoma, Renal cell
Case Reports
Family medical history
Heterotopic bone formation
Imaging
Kidney cancer
Medical imaging
Medicine
Medicine & Public Health
Obesity
Osseous metaplasia
Papillary thyroid microcancer
Patients
Radiology
Renal cell carcinoma
Risk factors
Surgery
Thyroid cancer
Thyroidectomy
Tumors
Urination
Urology
Weight control
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Summary:Backgrounds Although calcifications have been observed in various renal masses, osseous metaplasia has very rarely been reported. Here, we present a case of concomitant clear cell renal cell carcinoma with osseous metaplasia and papillary thyroid microcarcinoma. Case presentation A 52-year-old male was being investigated for having post-prandial gaseous abdominal distention. Computed tomography of the abdomen showed a heterogeneous mass lesion measuring 27 × 24 mm at the upper/mid pole of the right kidney. It also revealed two small (10 and 11 mm) benign bone islands in the body of the D4 and L4 vertebrae. The patient underwent a metastatic workup by computed tomography, which revealed a 93 × 35 mm mass in the left thyroid lobe with coarse calcification. A partial nephrectomy was planned for the renal mass, but the site of the mass deemed this impossible. Six months after the operation, the patient underwent total thyroidectomy. Histopathology of both tissue samples revealed concomitant clear cell renal cell carcinoma with heterotopic bone formation and papillary thyroid microcarcinoma. Conclusion Although rare, osseous metaplasia in renal cell carcinoma can occur and may indicate an early-stage carcinoma with a favorable prognosis.
ISSN:1961-9987
1110-5704
1961-9987
DOI:10.1186/s12301-023-00352-8