Association between imbalanced gut microecology and obstructive sleep apnea-associated hypertension: A prospective observational study

[...]we conducted an observational study to investigate whether OSA-induced gut microbiota dysbiosis contributes to the pathogenesis of OSAHTN. Patient inclusion criteria were (1) aged 20–50 years; (2) body mass index ≥24 kg/m2; (3) waist-to-hip ratio >0.9; (4) normal blood glucose, transaminase,...

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Bibliographic Details
Published in:Chinese medical journal 2024-12, Vol.137 (23), p.2893-2895
Main Authors: Ko, Chih-Yuan, Zhang, Li, Zhu, Zhixing, Zeng, Yiming
Format: Article
Language:English
Subjects:
Bacteria
Correspondence
Data analysis
Discriminant analysis
Gene amplification
Hypertension
Microbiota
Observational studies
Pathogenesis
Sleep apnea
Variance analysis
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Summary:[...]we conducted an observational study to investigate whether OSA-induced gut microbiota dysbiosis contributes to the pathogenesis of OSAHTN. Patient inclusion criteria were (1) aged 20–50 years; (2) body mass index ≥24 kg/m2; (3) waist-to-hip ratio >0.9; (4) normal blood glucose, transaminase, and creatinine concentrations; (5) completed collection of blood and stool; and (6) reliable data analysis. [...]the population of the investigated cohort was relatively small. [...]the mechanism of OSA-associated dysregulation in the gut microbiome that contributes to development of hypertension secondary to OSA requires further study.
ISSN:0366-6999
2542-5641
2542-5641
DOI:10.1097/CM9.0000000000003314