Case Report: Pleural effusion in Wilms tumor - always malignant? [version 1; peer review: awaiting peer review]

Wilms tumor (WT) is the most common renal malignancy seen in pediatric patients. Although lungs are the most common site of metastasis in Wilms tumor, non-malignant pleural effusion has been infrequently reported. Here, we report a case of an eleven-year-old female who presented with an abdominal ma...

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Bibliographic Details
Published in:F1000 research 2023, Vol.12, p.1056
Main Authors: Vagha, Keta, Zeeshan Jameel, Patel, Vagha, Jayant, Varma, Ashish, Rao, Rupesh
Format: Article
Language:English
Subjects:
Abdomen
Case Report
Case reports
Cellular biology
Chemotherapy
Child
Diaphragm (Anatomy)
eng
Female
Females
Hematology
Humans
Kidney Neoplasms - complications
Kidney Neoplasms - pathology
Liver
Lungs
Malignancy
Medical prognosis
Metastases
Metastasis
Patients
Pediatrics
Pleural effusion
Pleural Effusion - etiology
Pleural Effusion - pathology
Pleural Effusion, Malignant - etiology
Pleural Effusion, Malignant - pathology
pulmonary metastasis
Radiation therapy
Tumors
Wilms tumor
Wilms Tumor - complications
Wilms Tumor - pathology
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Summary:Wilms tumor (WT) is the most common renal malignancy seen in pediatric patients. Although lungs are the most common site of metastasis in Wilms tumor, non-malignant pleural effusion has been infrequently reported. Here, we report a case of an eleven-year-old female who presented with an abdominal mass and progressive breathlessness. On further evaluation, she was found to have a right-sided Wilms tumor with ipsilateral massive pleural effusion. The effusion resolved almost completely after four weeks of chemotherapy. We conclude that patients suffering from Wilms tumor presenting with pleural effusion need not be synonymous with metastatic disease and can have a favorable prognosis.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.138794.1