Therapeutic potential of berries in age-related neurological disorders

Aging significantly impacts several age-related neurological problems, such as stroke, brain tumors, oxidative stress, neurodegenerative diseases (Alzheimer's, Parkinson's, and dementia), neuroinflammation, and neurotoxicity. Current treatments for these conditions often come with side eff...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in pharmacology 2024-05, Vol.15, p.1348127-1348127
Main Authors: Norouzkhani, Narges, Afshari, Shaghayegh, Sadatmadani, Sayedeh-Fatemeh, Mollaqasem, Mohammad Mahdi, Mosadeghi, Shakila, Ghadri, Hani, Fazlizade, Safa, Alizadeh, Keyvan, Akbari Javar, Pouyan, Amiri, Hamidreza, Foroughi, Elaheh, Ansari, Arina, Mousazadeh, Kourosh, Davany, Bozorgmehr Abdullahzadeh, Akhtari Kohnehshahri, Ata, Alizadeh, Alaleh, Dadkhah, Parisa Alsadat, Poudineh, Mohadeseh
Format: Article
Language:English
Subjects:
age-related neurological disease
aging
berry fruits
complementary medicine
Pharmacology
treatment
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aging significantly impacts several age-related neurological problems, such as stroke, brain tumors, oxidative stress, neurodegenerative diseases (Alzheimer's, Parkinson's, and dementia), neuroinflammation, and neurotoxicity. Current treatments for these conditions often come with side effects like hallucinations, dyskinesia, nausea, diarrhea, and gastrointestinal distress. Given the widespread availability and cultural acceptance of natural remedies, research is exploring the potential effectiveness of plants in common medicines. The ancient medical system used many botanical drugs and medicinal plants to treat a wide range of diseases, including age-related neurological problems. According to current clinical investigations, berries improve motor and cognitive functions and protect against age-related neurodegenerative diseases. Additionally, berries may influence signaling pathways critical to neurotransmission, cell survival, inflammation regulation, and neuroplasticity. The abundance of phytochemicals in berries is believed to contribute to these potentially neuroprotective effects. This review aimed to explore the potential benefits of berries as a source of natural neuroprotective agents for age-related neurological disorders.
ISSN:1663-9812
1663-9812
DOI:10.3389/fphar.2024.1348127