Not only a bad guy:potential proneurogenic role of the RAGE/NF-κB axis in Alzheimer’s disease brain

<正>The receptor for advanced glycation endproducts(RAGE)is a receptor of the immunoglobulin superfamily of cell surface molecules which plays important contributions under both physiological and pathological conditions.Over the years extensive research work supported the detrimental ro...

Full description

Saved in:
Bibliographic Details
Published in:Neural regeneration research 2016-12, Vol.11 (12), p.1924-1925
Main Authors: Bortolotto, Valeria, Grilli, Mariagrazia
Format: Article
Language:English
Subjects:
Alzheimer's disease
Animal cognition
Laboratories
Ligands
Memory
Neurodegeneration
Neurogenesis
Pathology
Transgenic animals
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:<正>The receptor for advanced glycation endproducts(RAGE)is a receptor of the immunoglobulin superfamily of cell surface molecules which plays important contributions under both physiological and pathological conditions.Over the years extensive research work supported the detrimental role of RAGE in Alzheimer’s disease(AD)pathophysiology,ranging from its involvement in beta amyloid(Aβ)brain influx and clearance,
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.197130