Bacterial profile and antimicrobial susceptibility patterns in chronic suppurative otitis media at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

• Published in: BMC research notes 2019-07, Vol.12 (1), p.414-414, Article 414
• Main Authors: Molla, Rahel, Tiruneh, Moges, Abebe, Wondwossen, Moges, Feleke
• Format: Article
• Language: English
• Subjects: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents - pharmacology; Antibacterial agents; Antimicrobial susceptibility patterns; Bacteria; Bacteria - classification; Bacteria - drug effects; Bacteria - isolation & purification; Bacterial Infections - diagnosis; Bacterial Infections - drug therapy; Bacterial Infections - microbiology; Causes of; Cefepime; Chloramphenicol; Chronic Disease; Chronic suppurative otitis media; Ciprofloxacin; Ciprofloxacin - pharmacology; Clarithromycin; Clarithromycin - pharmacology; Drug therapy; Erythromycin; Ethiopia; Forecasts and trends; Hospitals, Special; Hospitals, University; Humans; Microbial drug resistance; Microbial Sensitivity Tests - methods; Norfloxacin - pharmacology; Otitis; Otitis media; Otitis Media, Suppurative - diagnosis; Otitis Media, Suppurative - drug therapy; Otitis Media, Suppurative - microbiology; Patient outcomes; Penicillins; Proteus mirabilis - drug effects; Proteus mirabilis - isolation & purification; Proteus mirabilis - physiology; Research Note; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - isolation & purification; Staphylococcus aureus - physiology; Tetracyclines; Tobramycin
• ISSN: 1756-0500; 1756-0500
• DOI: 10.1186/s13104-019-4452-4

This study aims to determine bacterial profile and antimicrobial susceptibility patterns of chronic suppurative otitis media in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. Sixty-two ear swabs were collected and 74 bacterial isolates were identified, of which 48 (77.4%) sample with mono-microbial growth, 11 (17.8%) with polymicrobial growth and the remaining 3 (4.8%) show no growth. The most common isolates were Proteus mirabilis 16 (21.6%), followed by S. aureus 12 (16.2%), Klebsiella spp. 10 (13.5%) and Providencia spp. 11 (14.9%). Proteus mirabilis was 100% susceptible to norfloxacin and ciprofloxacin while 87.5% of the isolates were susceptible to cefixime and gentamicin. S. aureus was 83.3% susceptible to gentamicin and clarithromycin, while 75% of the isolates were susceptible to amoxicillin-clavulanic acid and chloramphenicol, however, 66.7% the isolates were susceptible to ciprofloxacin, norfloxacin and erythromycin. The overall prevalence of multidrug resistance in the current study was 35 (47.3%). In this study P. mirabilis, S. aureus, Providencia spp., and Klebsiella spp. were the most common bacterial isolate and all Gram negative isolates were susceptible to ciprofloxacin and norfloxacin. Amoxicillin-clavulanic acid, gentamicin, chloramphenicol, clarithromycin and tobramycin were relatively effective against Gram positive bacteria.