Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes

Abstract Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in c...

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Bibliographic Details
Published in:Epilepsy & behavior case reports 2018-01, Vol.9, p.12-18
Main Authors: Taraschenko, Olga, Pedavally, Swetha, Samson, Kaeli K, Puccioni, Mark J, Madhavan, Deepak
Format: Article
Language:English
Subjects:
Corpus callosotomy
Epilepsy surgery
Intracranial EEG
Neurology
Refractory seizures
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Summary:Abstract Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in combination with focal resection, to determine the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic–clonic or tonic seizures. Invasive EEG prior to CC did not refine the prediction of postsurgical seizure outcomes in patients with inconclusive scalp EEG.
ISSN:2213-3232
2213-3232
DOI:10.1016/j.ebcr.2017.12.001