Aortic pulse wave velocity and its relationship with transaortic flow and gradients in patients with severe aortic stenosis undergoing aortic valve replacement

Low-flow, low-gradient severe aortic stenosis (LFLGAS) is a common clinical entity and is associated with poor prognosis. Increased left ventricular (LV) afterload is one of the mechanisms contributing to low LV stroke volume index (SVi) in these patients. Aortic stiffness is an important determinan...

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Bibliographic Details
Published in:Indian heart journal 2020-09, Vol.72 (5), p.421-426
Main Authors: Ranjan, Shraddha, Grewal, Hardeep Kaur, Kasliwal, Ravi R., Trehan, Naresh, Bansal, Manish
Format: Article
Language:English
Subjects:
Arterial stiffness
Low-flow aortic stenosis
Low-gradient aortic stenosis
Original
Paradoxical low-flow low-gradient aortic stenosis
Valvulo-arterial impedance
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Summary:Low-flow, low-gradient severe aortic stenosis (LFLGAS) is a common clinical entity and is associated with poor prognosis. Increased left ventricular (LV) afterload is one of the mechanisms contributing to low LV stroke volume index (SVi) in these patients. Aortic stiffness is an important determinant of LV afterload, but no previous study has evaluated its relationship with LVSVi in patients with AS. Fifty-seven patients (mean age 66 ± 8 years, 71.9% men) with severe AS [aortic valve area (AVA) 
ISSN:0019-4832
2213-3763
DOI:10.1016/j.ihj.2020.06.010