Regression of cardiac angiosarcoma in a 17-year-old: a percutaneous biopsy effect

Cardiac angiosarcoma is a very rare and aggressive primary cardiac tumor associated with poor prognosis. Diagnosis is often delayed due to non-specific symptoms, with most cases involving metastases at the time of diagnosis. We describe a unique case of apparent tumor regression of cardiac angiosarc...

Full description

Saved in:
Bibliographic Details
Published in:Cardio-oncology (London, England) England), 2024-07, Vol.10 (1), p.45-5, Article 45
Main Authors: Sharrack, Noor, Parent, Martine, Lethaby, Christopher, Rosendahl, Ulrich, Lyon, Alexander R, Farooq, Maryum, Jamil, Haqeel, Greenwood, John P, Plein, Sven, Kidambi, Ananth
Format: Article
Language:English
Subjects:
Biopsy
Cardiology
Cardiovascular Magnetic Resonance (CMR)
Case Report
Case reports
Lymphoma
Medical prognosis
Melanoma
Metastasis
Myocarditis
Pain
Percutaneous biopsy
Pericarditis
Primary cardiac angiosarcoma (PCAS)
Radiation therapy
Sarcoma
Tumor regression
Tumors
Veins & arteries
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cardiac angiosarcoma is a very rare and aggressive primary cardiac tumor associated with poor prognosis. Diagnosis is often delayed due to non-specific symptoms, with most cases involving metastases at the time of diagnosis. We describe a unique case of apparent tumor regression of cardiac angiosarcoma post percutaneous biopsy. A young male was admitted with suspected pericarditis. Echocardiogram revealed a pericardial mass. Cardiovascular magnetic resonance (CMR) suggested primary cardiac malignancy. Percutaneous biopsy was inconclusive, with subsequent CMR demonstrating apparent tumor regression. Interval imaging revealed further tumor growth, and surgical biopsy revealed primary cardiac angiosarcoma (PCAS). Causes of tumor regression following percutaneous biopsy are discussed. Cases of suspected primary cardiac malignancy require careful follow up with serial multimodality imaging. Percutaneous biopsy effects should be considered in cases of tumor regression, and serial imaging should be planned afterwards.
ISSN:2057-3804
2057-3804
DOI:10.1186/s40959-024-00239-9