Solitary pancreatic metastasis from breast cancer: case report and review of literature

Pancreatic metastases from primary malignant tumors at other sites are rare, constituting about 2% of the neoplasms that affect the pancreas. Pancreatic metastasis from breast cancer is extremely rare and difficult to diagnose, because its clinical and radiological presentation is similar to that of...

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Bibliographic Details
Published in:São Paulo medical journal 2019-03, Vol.137 (2), p.201-205
Main Authors: Apodaca-Rueda, Márcio, Chaim, Fábio Henrique Mendonça, Garcia, Milena da Silva, Saito, Helena Paes de Almeida de, Gestic, Martinho Antonio, Utrini, Murillo Pimentel, Callejas-Neto, Francisco, Chaim, Elinton Adami, Cazzo, Everton
Format: Article
Language:English
Subjects:
Breast neoplasms
Carcinoma, ductal, breast
Case Report
MEDICINE, GENERAL & INTERNAL
Neoplasm metastasis
Pancreas
Pancreatic neoplasms
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Summary:Pancreatic metastases from primary malignant tumors at other sites are rare, constituting about 2% of the neoplasms that affect the pancreas. Pancreatic metastasis from breast cancer is extremely rare and difficult to diagnose, because its clinical and radiological presentation is similar to that of a primary pancreatic tumor. A 64-year-old female developed a lesion in the pancreatic tail 24 months after neoadjuvant therapy, surgery and adjuvant radiation therapy for right-side breast cancer (ductal carcinoma). She underwent distal pancreatectomy with splenectomy and left adrenalectomy, and presented an uneventful outcome. The immunohistochemical analysis on the surgical specimen suggested that the lesion originated from the breast. In cases of pancreatic lesions detected in patients with a previous history of breast neoplasm, the possibility of pancreatic metastasis should be carefully considered.
ISSN:1516-3180
1806-9460
1806-9460
DOI:10.1590/1516-3180.2017.0144260617