Preliminary findings on the expression of plasma CD63, CD62P, and PAI 1 in patients with acute cerebral infarction

To investigate the expression and clinical significance of lysosomal granule glycoprotein 63 (CD63), P-selectin (CD62P) and endothelial cell plasminogen activator inhibitor (PAI-1) in patients with acute cerebral infarction. A total of 106 patients with acute cerebral infarction (ACI) admitted to ou...

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Bibliographic Details
Published in:European journal of inflammation 2018, Vol.16
Main Authors: Xu, Donghua, Ren, Zhanyun, Shi, Junfeng, Wang, Guoxiang, Qin, Yaxin, Zhang, Jin, Chen, Chengfang, Tang, Wuzhuang
Format: Article
Language:English
Subjects:
Health risk assessment
Patients
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Summary:To investigate the expression and clinical significance of lysosomal granule glycoprotein 63 (CD63), P-selectin (CD62P) and endothelial cell plasminogen activator inhibitor (PAI-1) in patients with acute cerebral infarction. A total of 106 patients with acute cerebral infarction (ACI) admitted to our hospital from January to July in 2017 were selected as the patient group; 80 healthy subjects for physical examination in our hospital were selected as the control group. The expression levels of serum CD63, CD62P, and PAI-1 of the subjects were detected. The levels of CD63, CD62P, and PAI-1 in the serum of the patient group were significantly higher than those in the control group. There was a positive correlation between serum CD63 and CD62P (r = 0.672, P 
ISSN:2058-7392
1721-727X
2058-7392
DOI:10.1177/2058739218819674