Application of Mitomycin C after dilation of an anastomotic stricture in a newborn with necrotizing enterocolitis

Abstract Necrotizing enterocolitis (NEC) is a common life-threatening condition in premature infants. Bacterial translocation, localized inflammation and subsequent perforation often require surgery for source control and definitive treatment. Small and large intestinal strictures may result from ei...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pediatric surgery case reports 2016, Vol.4 (C), p.49-51
Main Authors: Green, Jonathan, Schlieve, Christopher, Hirsh, Michael P, Nazarey, Pradeep, Aidlen, Jeremy T
Format: Article
Language:English
Subjects:
Mitomycin C
Necrotizing enterocolitis
Stricture
Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Necrotizing enterocolitis (NEC) is a common life-threatening condition in premature infants. Bacterial translocation, localized inflammation and subsequent perforation often require surgery for source control and definitive treatment. Small and large intestinal strictures may result from either creation of a surgical anastomosis or the disease process itself. Current methods to treat strictures include, balloon dilation and surgical resection with or without anastomosis. We report the diagnosis and surgical management of a premature infant treated for NEC, who developed an anastomotic stricture and was successfully treated with topical Mitomycin C after balloon stricturoplasty.
ISSN:2213-5766
2213-5766
DOI:10.1016/j.epsc.2015.12.001