Symptomatic sinus bradycardia: A rare adverse effect of intravenous ondansetron

Ondansetron is a serotonin receptor antagonist which has been used frequently to reduce the incidence of post-operative nausea and vomiting in laparoscopic surgery. It has become very popular drug for the prevention of post-operative nausea and vomiting due to its superiority in-terms of efficacy as...

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Bibliographic Details
Published in:Saudi journal of anaesthesia 2011-01, Vol.5 (1), p.96-97
Main Authors: Moazzam, Md Shahnawaz, Nasreen, Farah, Bano, Shahjahan, Amir, Syed Hussain
Format: Article
Language:English
Subjects:
Adverse effect
Bradycardia
Cardiac arrhythmia
Case Report
Complications and side effects
Gallbladder diseases
Heart rate
Nausea
Ondansetron
Serotonin
sinus bradycardia
Sinuses
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Summary:Ondansetron is a serotonin receptor antagonist which has been used frequently to reduce the incidence of post-operative nausea and vomiting in laparoscopic surgery. It has become very popular drug for the prevention of post-operative nausea and vomiting due to its superiority in-terms of efficacy as well as lack of side effects and drug interactions. Although cardiovascular adverse effects of this drug are rare, we found a case of symptomatic sinus bradycardia in a 43-year-old female patient, going for laparoscopic cholecystectomy, who developed the same after she was given intravenous ondansetron in operation theater during premedication. Hence, we report this case, as the rare possibility of encountering bradycardia effect after intravenous administration of ondansetron should be born in mind.
ISSN:1658-354X
0975-3125
DOI:10.4103/1658-354X.76492