Foveal hypoplasia and characteristics of optical components in patients with familial exudative vitreoretinopathy and retinopathy of prematurity

• Published in: Scientific reports 2022-05, Vol.12 (1), p.7694-7694, Article 7694
• Main Authors: Chen, Pei-Ying, Kang, Eugene Yu-Chuan, Chen, Kuan-Jen, Ling, Xiao Chun, Chang, Yin-Hsi, Wang, Nan-Kai, Liu, Laura, Chen, Yen-Po, Hwang, Yih-Shiou, Lai, Chi-Chun, Wu, Wei-Chi
• Format: Article
• Language: English
• Subjects: 692/53/2422; 692/698/1688/512/2613/1786; Acuity; Age; Eye; Familial Exudative Vitreoretinopathies; Familial exudative vitreoretinopathy; Gestational Age; Hospitals; Humanities and Social Sciences; Humans; Hypoplasia; Infant, Newborn; multidisciplinary; Myopia; Ophthalmology; Optical Devices; Patients; Premature birth; Retina; Retinal detachment; Retinopathy; Retinopathy of Prematurity; Retrospective Studies; Science; Science (multidisciplinary); Statistical analysis; Tomography, Optical Coherence; Vision Disorders
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-11455-7

There has been limited research regarding the status of foveal hypoplasia and the characteristics of the optical components of the eye in patients with familial exudative vitreoretinopathy (FEVR) and retinopathy of prematurity (ROP). In this retrospective cohort study, patients were classified into five groups: patients with stage 1 and 2 FEVR (FEVR group), patients with ROP who received treatment (treated ROP group), patients with ROP who did not receive treatment (untreated ROP group), patients without ROP who had been born preterm (preterm group), and healthy patients who had been born at term (full-term group). Visual acuity, refractive error, characteristics of the optical components, and features of the fovea were compared. In total, 179 eyes from 100 patients were included. Patients in the FEVR group had the highest degrees of myopia ( p