Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis

Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The...

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Bibliographic Details
Published in:PloS one 2023-10, Vol.18 (10), p.e0292974-e0292974
Main Authors: Curran, Jeffrey, Ross-White, Amanda, Sibley, Stephanie
Format: Article
Language:English
Subjects:
Atrial fibrillation
Diagnosis
Medicine and Health Sciences
Physical Sciences
Prevention
Research and Analysis Methods
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Summary:Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The objective of this study is to summarize studies examining magnesium versus placebo in the prevention of NOAF outside the setting of cardiac surgery. Use of magnesium did not reduce the incidence of NOAF, however these studies represent diverse groups and are hindered by significant bias. Further studies are necessary to determine if there is benefit to magnesium prophylaxis for NOAF in non-cardiac surgery patients.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0292974