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Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis
Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The...
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Published in: | PloS one 2023-10, Vol.18 (10), p.e0292974-e0292974 |
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description | Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The objective of this study is to summarize studies examining magnesium versus placebo in the prevention of NOAF outside the setting of cardiac surgery. Use of magnesium did not reduce the incidence of NOAF, however these studies represent diverse groups and are hindered by significant bias. Further studies are necessary to determine if there is benefit to magnesium prophylaxis for NOAF in non-cardiac surgery patients. |
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Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The objective of this study is to summarize studies examining magnesium versus placebo in the prevention of NOAF outside the setting of cardiac surgery. Use of magnesium did not reduce the incidence of NOAF, however these studies represent diverse groups and are hindered by significant bias. Further studies are necessary to determine if there is benefit to magnesium prophylaxis for NOAF in non-cardiac surgery patients.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0292974</identifier><language>eng</language><publisher>San Francisco, CA USA: Public Library of Science</publisher><subject>Atrial fibrillation ; Diagnosis ; Medicine and Health Sciences ; Physical Sciences ; Prevention ; Research and Analysis Methods</subject><ispartof>PloS one, 2023-10, Vol.18 (10), p.e0292974-e0292974</ispartof><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Curran et al 2023 Curran et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c567t-63fa8d9173a059a6f2b835012104488aec9934d410b0dc53749850952a1a84f53</cites><orcidid>0000-0003-2229-9747</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602269/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602269/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids></links><search><contributor>Ibrahim, Ramzi</contributor><creatorcontrib>Curran, Jeffrey</creatorcontrib><creatorcontrib>Ross-White, Amanda</creatorcontrib><creatorcontrib>Sibley, Stephanie</creatorcontrib><title>Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis</title><title>PloS one</title><description>Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. Magnesium prophylaxis has been shown to reduce incidence of AF in cardiac surgery patients, however, evidence outside this population is limited. The objective of this study is to summarize studies examining magnesium versus placebo in the prevention of NOAF outside the setting of cardiac surgery. Use of magnesium did not reduce the incidence of NOAF, however these studies represent diverse groups and are hindered by significant bias. Further studies are necessary to determine if there is benefit to magnesium prophylaxis for NOAF in non-cardiac surgery patients.</description><subject>Atrial fibrillation</subject><subject>Diagnosis</subject><subject>Medicine and Health Sciences</subject><subject>Physical Sciences</subject><subject>Prevention</subject><subject>Research and Analysis Methods</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqNkl2L1DAUhosouK7-Ay8KguhFx3y1TbyRYfFjYGXBrzsJp2naydAmY5Lu7vx7051h2YIXkoskJ895c3LyZtlLjFaY1vjdzk3ewrDaO6tXiAgiavYoO8OCkqIiiD5-sH6aPQthh1BJeVWdZb-_Qm91MNOY773bbw8D3JqQuy63-qZwNuiYQ_QGhrwzjTfDANE4-z5f5-EQoh7TVuVeXxt9k4Nt81FHKCBVcwgmPM-edDAE_eI0n2c_P338cfGluLz6vLlYXxaqrOpYVLQD3gpcU0ClgKojDaclwgQjxjgHrYSgrGUYNahVJa2Z4CUSJQEMnHUlPc82R93WwU7uvRnBH6QDI-8CzvcSfCp00JIwqJsm3UuakjUqtQorxqjo2haXnIqk9eGotZ-aUbdK2-hhWIguT6zZyt5dS4wqREg1K7w5KXj3Z9IhytEEpVPrrHZTkISn19WcVTShr45oD6k2YzuXJNWMy3VdIyoYEixRq39QabR6NCp9emdSfJHwdpGQmKhvYw9TCHLz_dv_s1e_luzrB-xWwxC3wQ3TbImwBNkRVN6F4HV33z-M5OxZefKsnD0rT56lfwHgfOAV</recordid><startdate>20231026</startdate><enddate>20231026</enddate><creator>Curran, Jeffrey</creator><creator>Ross-White, Amanda</creator><creator>Sibley, Stephanie</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2229-9747</orcidid></search><sort><creationdate>20231026</creationdate><title>Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis</title><author>Curran, Jeffrey ; Ross-White, Amanda ; Sibley, Stephanie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c567t-63fa8d9173a059a6f2b835012104488aec9934d410b0dc53749850952a1a84f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Atrial fibrillation</topic><topic>Diagnosis</topic><topic>Medicine and Health Sciences</topic><topic>Physical Sciences</topic><topic>Prevention</topic><topic>Research and Analysis Methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Curran, Jeffrey</creatorcontrib><creatorcontrib>Ross-White, Amanda</creatorcontrib><creatorcontrib>Sibley, Stephanie</creatorcontrib><collection>CrossRef</collection><collection>Opposing Viewpoints Resource Center</collection><collection>Gale In Context: Science</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals (Open Access)</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Curran, Jeffrey</au><au>Ross-White, Amanda</au><au>Sibley, Stephanie</au><au>Ibrahim, Ramzi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis</atitle><jtitle>PloS one</jtitle><date>2023-10-26</date><risdate>2023</risdate><volume>18</volume><issue>10</issue><spage>e0292974</spage><epage>e0292974</epage><pages>e0292974-e0292974</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Atrial fibrillation (AF) is the most common cardiac arrhythmia in intensive care units (ICU) and is associated with increased morbidity and mortality. 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subjects | Atrial fibrillation Diagnosis Medicine and Health Sciences Physical Sciences Prevention Research and Analysis Methods |
title | Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis |
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