Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient

Pseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas...

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Bibliographic Details
Published in:Data in brief 2020-10, Vol.32, p.106071-106071, Article 106071
Main Authors: Srivastava, Prakhar, Gomathinayagam, Sankaranarayanan, Easwaran, Nalini, Sankar, Gowri, Padmavathi, E., Shankar, Manoharan, Gothandam, Kodiveri M., Sivashanmugam, Karthikeyan
Format: Article
Language:English
Subjects:
Biochemistry, Genetics and Molecular Biology
Biofilm
Diabetic foot ulcer
Efflux pump
Homoserine lactone
Quorum sensing
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Summary:Pseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas aeruginosa isolates (VIT PC 7 and VIT PC 9) displaying homoserine lactone, rhamnolipid producing, biofilm phenotype and antibiotic resistance genes related to carbapenem, aminoglycoside, beta- lactamase and tetracycline resistance. The whole genome sequencing library was prepared according to the Oxford Nanopore's SQK-LSK108 kit protocol on Oxford Nanopore's Minion platform. The 7.1 Mb and 6.3-Mb draft genome sequence with GC content of 65.8% and 66.4% respectively provides insight into their resistance mechanism and virulence factors.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2020.106071