Fine needle aspiration diagnosis of Rosai-Dorfman Disease involving thyroid

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy is a rare disease involving the lymph nodes. Extranodal RDD involving the thyroid is extremely rare. So far, six cases of RDD involving thyroid have been reported in the literature; all have occurred in femal...

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Bibliographic Details
Published in:Journal of cytology 2012-01, Vol.29 (1), p.83-85
Main Authors: Vujhini, Sudhir Kumar, Kolte, Sachin S, Satarkar, Rahul N, Srikanth, Shastry
Format: Article
Language:English
Subjects:
Biopsy, Needle
Care and treatment
Case Report
Case studies
Diagnosis
Females
Fever
Fine needle aspiration cytology
Rosai-Dorfman disease
thyroid
Health aspects
Histiocytosis
Lymphocytes
Lymphoma
Patient outcomes
Plasma
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Summary:Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy is a rare disease involving the lymph nodes. Extranodal RDD involving the thyroid is extremely rare. So far, six cases of RDD involving thyroid have been reported in the literature; all have occurred in females with a mean age of 56.3 years. Clinically, radiologically and cytologically, all the cases were initially diagnosed as thyroid malignancies with lymph nodal metastasis. The final diagnosis was made histologically only after total thyroidectomy. We herein, present a seventh case of RDD involving the thyroid in a 15-year-old female, diagnosed first on fine needle aspiration cytology (FNAC). We conclude that FNAC is a useful diagnostic procedure for RDD involving thyroid; it can avoid an unnecessary thyroidectomy.
ISSN:0970-9371
0974-5165
DOI:10.4103/0970-9371.93239