Pre- and post-bronchodilator airway obstruction are associated with similar clinical characteristics but different prognosis - report from a population-based study

According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as...

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Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease 2017-01, Vol.12, p.1269-1277
Main Authors: Sawalha, Sami, Hedman, Linnea, Rönmark, Eva, Lundbäck, Bo, Lindberg, Anne
Format: Article
Language:English
Subjects:
Age
Aged
Airway management
Airway obstruction
Angina pectoris
Anxiety
Asthma
Body mass index
Bronchodilator Agents - administration & dosage
Cardiovascular disease
Care and treatment
chronic airflow obstructions
Chronic obstructive lung disease
Comorbidity
Complications and side effects
copd
Councils
Diabetes
Diagnosis
Dyspnea
epidemiology
Female
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
follow-up
Forced Expiratory Volume
Gender differences
health
Heart
Humans
Kaplan-Meier Estimate
Lung - physiopathology
Lung diseases
lung-disease
Lungmedicin och allergi
Male
Medical prognosis
Medical research
Middle Aged
Mortality
northern-sweden
Original Research
Population
Population-based studies
Predictive Value of Tests
prevalence
Prognosis
Proportional Hazards Models
Public Health, Global Health, Social Medicine and Epidemiology
Pulmonary Disease, Chronic Obstructive - diagnosis
Pulmonary Disease, Chronic Obstructive - mortality
Pulmonary Disease, Chronic Obstructive - physiopathology
pulmonary-disease
Respiratory Medicine and Allergy
respiratory symptoms
Respiratory System
Rhinitis
Risk Factors
Smoking
Spirometry
Spirometry - methods
Time Factors
Values
Vital Capacity
Womens health
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Description
Summary:According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as mortality, between subjects with airway obstruction divided into pre- but not post-BD obstruction, post-BD airway obstruction (COPD), and subjects without airway obstruction. In 2002-2004, four adult population-based cohorts were reexamined with spirometry and structured interview. Subjects with airway obstruction, with a ratio of forced expiratory volume in 1 s to (forced) vital capacity
ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S127923